Modern trends in psychopathology are the increase in the number of patients who need psychiatric or psychological assistance, inadequate staffing of the mental health system, low psychological culture of the population, lack of a system of early detection of predisposition to psychopathology. The review is devoted to one of the unsolved problems - this is a problem of autoaggressive behavior, which manifests itself in self-blame, self-abuse, self-injury, suicide, self-destructive behavior (drunkenness, alcoholism, drug addiction, risky sexual behavior, choice of extreme sports, dangerous occupations, provoking behavior), and it is one of the most relevant in the field of mental health. The risk factors for self-harm, both in the clinical and in the conventionally normal population, are usually considered within two large groups: a) external (environmental or psychosocial factors and traumatic events), b) internal (personal) factors and their interaction. Although most of the self-harm observed in normative mental development in adolescence, adolescence and young age is preclinical and is nonincidental, suicidal intentions can’t be completely ruled out, which requires mandatory testing and clarification of the possible suicide risk in self-destructive behavior within the planned therapy and the selection of relevant targets psychological correction. Since the main contingent requiring registration and assistance is someone who has committed a suicidal attempt, the prevention of a repeated autoaggressive action is the main task of the work of specialists providing psychological and medical and social assistance in the post-suicide period