Annotation. The article is devoted to the study of the functioning of the cardiovascular system of junior year students of a higher medical education institution depending on the level of physical health under different conditions of study (during regular studies and during exams). The study was conducted on the basis of the National Pirogov Memorial Medical University, in which 230 students of the medical faculty aged 17 to 22 years participated. The assessment of the level of physical health was carried out according to the method of quantitative express assessment of the level of somatic health (Apanasenko G. L.). To analyze the functioning of the cardiovascular system, Robinson's index, APs, APd, heart rate were determined using standard methods. Statistical data processing was carried out by the “Statistica 6.0” program. Based on the results of the study, it was established that out of 230 students of the first year, a high level of physical health was not registered at all, 10 people had an above average level of physical health, which is 4.3% of the total number of students. 22.6% of students have average physical health, 31.7% below average, and 41.3% low – 41.3%. The functioning of the cardiovascular system in students in the intersession and session periods was also analyzed. It was found that with a decrease in the level of physical health, the level of efficiency of the functioning of the cardiovascular system decreases, the values of APs, APd, heart rate increase in girls and boys, especially during intense mental loads (sessions). The significance of the difference between the compared groups was p<0.05, p<0.01, p<0.001. Students who took part in the psychocorrective program mastered self-control skills and had significantly better values of the indicators of cardiovascular system activity that were studied, in relation to groups of untrained individuals, both under normal educational conditions and under increased intellectual loads (р<0.05, p<0.01).