Psychological Functioning in Children With Crohn's Disease and Ulcerative Colitis: Implications for Models of Psychobiological Interaction

Wood, Beatrice L.; Watkins, John B.; Boyle, John T.; Nogueira, José; Zimand, Elana; Carroll, Lisa

doi:10.1097/00004583-198709000-00027

Cited by 72 publications

(46 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The current results differ from the two studies that compared children with IBD to healthy children. In contrast to the current findings, Wood et al (16) reported that children with IBD had significantly more behavioral/emotional symptoms than a sibling comparison group. Similarly, using the same small sample of children with IBD and healthy and ill comparison groups, Engstrom (17)(18)(19) and Engstrom and Lindquist (20) reported that children with IBD had significantly more behavioral/emotional symptoms than healthy children.…”

Section: Discussioncontrasting

confidence: 99%

See 1 more Smart Citation

Long-Term Psychosocial Outcomes Reported by Children and Adolescents with Inflammatory Bowel Disease

Mackner

Crandall

2005

Am J Gastroenterology

103

106

View full text Add to dashboard Cite

show abstract

Section: Discussioncontrasting

confidence: 99%

“…Of the few previous studies that examined specific behavioral and emotional symptoms using well-validated parentor child-report measures, four reported normative T scores within the normal range (13)(14)(15)(16), which is similar to the current results. However, most of those studies did not employ healthy comparison groups.…”

Section: Discussionsupporting

confidence: 87%

Long-Term Psychosocial Outcomes Reported by Children and Adolescents with Inflammatory Bowel Disease

Mackner

Crandall

2005

Am J Gastroenterology

103

106

View full text Add to dashboard Cite

show abstract

“…Four studies, however, have reported no significant relationship between emotional symptoms and disease factors such as validated disease activity scores, growth delay, and/or frequency of relapse [11,15,16 ,17]. Three studies found significant relationships with only some disease-severity indicators and/or with only specific symptoms of depression [5,17,18]. For example, one study [5] found significant differences in depressive symptoms between the moderate/severe disease activity and the remission groups, but not between these categories and the mild-disease group.…”

Section: Behavioral/emotional Functioningmentioning

confidence: 99%

Psychological factors affecting pediatric inflammatory bowel disease

Mackner

Crandall

2007

Current Opinion in Pediatrics

View full text Add to dashboard Cite

show abstract

“…This measure captures both parent and child perspectives on child HRQoL, takes less than 5 minutes to complete, comes in English and Spanish versions, and demonstrates high reliability and validity. Both child self-report and parent proxy report come in 3 forms, based on patient age (5)(6)(7)(8)(9)(10)(11)(12), and 13-18 years) to account for developmental differences in responses. We used only the last 2 child and youth forms in this study.…”

Section: Generic Quality Of Lifementioning

confidence: 99%

“…Adults with Crohn disease (CD) generally report worse HRQoL than those with ulcerative colitis (UC), with HRQoL also worse with active disease than with disease in remission (6). Previous pediatric studies have focused mainly on psychosocial factors as they relate to illness among children and adolescents with IBD, and have yielded inconsistent findings depending on the comparison group (7)(8)(9). Studies comparing children and adolescents with IBD with control populations have, as with other chronic conditions, indicated higher rates of psychological disturbance, including especially anxiety and depression, and problems in social functioning and self-esteem (10-12).…”

mentioning

confidence: 99%

Measuring quality of life in pediatric patients with inflammatory bowel disease: psychometric and clinical characteristics

2009

Primary Health Care

View full text Add to dashboard Cite

Objective-To extend development of a pediatric inflammatory bowel disease (IBD) healthrelated quality of life (HRQoL) measure by determining its factor structure and associations of factors with generic HRQoL measures and clinical variables.Patients and Methods-Cross-sectional survey of children and adolescents ages 8 years to 18 years and their parents attending any of 6 US IBD centers, recruited from either existing registry of age-eligible subjects or visits to participating centers. The survey included generic (Pediatric Quality of Life Inventory) and IBD-specific (Impact Questionnaire) quality of life measures, disease activity, and other clinical indicators. We carried out factor analysis of Impact responses, comparing resulting factors with results on the generic HRQoL and the clinical measures.Results-We included 220 subjects (161 with Crohn disease and 59 with ulcerative colitis). Initial confirmatory factor analysis did not support the 6 proposed Impact domains. Exploratory factor analysis indicated 4 factors with good to excellent reliability for IBD responses: general well-being and symptoms, emotional functioning, social interactions, and body image. Two items did not load well on any factor. The 4 factors correlated well with the Pediatric Quality of Life Inventory and subscales. Children with higher disease activity scores and other indicators of clinical activity reported lower HRQoL.Conclusions-This study provides further characteristics of a HRQoL measure specific to pediatric IBD and indicates ways to score the measure based on the resulting factor structure. The measure correlates appropriately with generic HRQoL measures and clinical severity indicators. KeywordsCrohn disease; Ulcerative colitis; Well-being; Disease activity; Functional status © 2008 by European Society for Pediatric Gastroenterology, Hepatology, and Nutrition and North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition Address correspondence and reprint requests to James Perrin, MD, 50 Staniford Street, Suite 901, Boston, MA 02114 (jperrin@partners.org). The authors report no conflicts of interest. The goals of this study, involving a consortium of pediatric IBD centers, were to extend evaluation of the Impact Questionnaire in a larger population and through factor analysis. We expected that confirmatory factor analysis would support the original 6 domains proposed by the developers of the measure. In addition, we compared the IBD-specific QoL findings with those on a more generic HRQoL measure and with measures of severity of IBD, as further validation of the measure. We hypothesized that the IBD measure would correlate well with broader measures of HRQoL. Furthermore, we expected that children and adolescents with more severe or active disease would report lower QoL. Based on previous research, we also expected that subjects with CD would report worse HRQoL. NIH Public Access PATIENTS AND METHODSThis study sampled children diagnosed with UC or CD followed at 1 of 6 pediatric gastroenterolog...

show abstract

Psychological Functioning in Children With Crohn's Disease and Ulcerative Colitis: Implications for Models of Psychobiological Interaction

Cited by 72 publications

References 25 publications

Long-Term Psychosocial Outcomes Reported by Children and Adolescents with Inflammatory Bowel Disease

Long-Term Psychosocial Outcomes Reported by Children and Adolescents with Inflammatory Bowel Disease

Psychological factors affecting pediatric inflammatory bowel disease

Measuring quality of life in pediatric patients with inflammatory bowel disease: psychometric and clinical characteristics

Contact Info

Product

Resources

About