Psychological impact of acne on 21st-century adolescents: decoding for better care

Revol, Olivier; Milliez, N.; Gerard, Dava

doi:10.1111/bjd.13749

Cited by 49 publications

(47 citation statements)

References 32 publications

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“… 15 Isotretinoin, which is used to treat moderate-to-severe acne has been known to be teratogenic and can contribute to cheilitis, dermatitis, arthralgia, increased liver enzymes, cholesterol levels, depression, and even attempted suicide. 3 , 16 – 18 These large numbers of potential adverse events can scare patients from even starting the medication. They may also reduce patients’ use and if they occur, may cause patients to discontinue treatment altogether.…”

Section: Discussionmentioning

confidence: 99%

“…Acne vulgaris is a common chronic inflammatory disease that affects 45 million people in the USA. 1 Acne negatively affects the quality of life – as measured by low self-esteem, increased social and emotional anxiety 2 , 3 – and imposes a considerable financial toll. 4 Annually, US consumers spend $1.2 billion on acne medications, 1 $233 per patient on prescribed acne treatments.…”

Section: Introductionmentioning

confidence: 99%

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Interventions to increase adherence to acne treatment

Tuchayi¹,

Alexander²,

Nadkarni³

et al. 2016

PPA

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BackgroundAdherence to acne medication is poor and is a major reason why treatment plans are ineffective. Recognizing solutions to nonadherence is critical.ObjectiveThe purpose of this study is to describe the hurdles associated with acne nonadherence and to provide mechanisms on how to ameliorate them.MethodsPubMed database was searched. Of the 419 search results, 29 articles were reviewed to identify hurdles to adherence and corresponding solutions.ResultsHurdles to primary nonadherence where the medication is not even started, include lack of knowledge, confusion about usage, weak physician–patient relationship, fear of adverse reactions, and cost. Secondary nonadherence hurdles where the medication is started but is not taken as directed include lack of results, complex regimens, side effects, busy lifestyle, forgetfulness, inconvenience, and psychiatric comorbidity. Solutions to these hurdles include treatment simplification, technology, and dynamic education.LimitationsAdherence is affected by numerous factors, but available literature analyzing acne adherence and interventions to improve adherence to treatment is limited.ConclusionThere are several hurdles in adhering to acne treatment. Recognition of these hurdles and finding appropriate solutions may be as important to treatment outcomes as choosing the right medication to prescribe.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Interventions to increase adherence to acne treatment

Tuchayi¹,

Alexander²,

Nadkarni³

et al. 2016

PPA

View full text Add to dashboard Cite

show abstract

“…Recent investigations highlight important psychiatric comorbidities – specifically, depression and suicidal risk – affecting a large proportion of patients with acne. The association of ‘problem’ acne with increased risk of anxiety, depression and suicidal ideation has been investigated in several studies in adolescents, and is addressed elsewhere in this supplement …”

Section: Psychological Impact Of Acnementioning

confidence: 99%

A global perspective on the epidemiology of acne

2015

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SummaryAcne is estimated to affect 9Á4% of the global population, making it the eighth most prevalent disease worldwide. Epidemiological studies have demonstrated that acne is most common in postpubescent teens, with boys most frequently affected, particularly with more severe forms of the disease. This paper aims to provide an update on the epidemiology of acne worldwide. Recent general and institutional studies from around the world have shown that the prevalence of acne is broadly consistent globally (with the exception of specific populations, which are discussed). However, this review highlights that there is a wide range of disparate outcome measures being applied in epidemiology studies, and we emphasize the need to develop a widely accepted, credible, standard assessment scale to address this in the future. In addition we discuss special populations, such as those devoid of acne, as well as the impact of potential determinants of acne on disease epidemiology.Acne vulgaris, or acne, is a common condition with a wide range of potential harms and associated costs. The former include symptomatic discomfort, scarring, emotional and psychosocial distress, occupational consequences and potential psychiatric disturbances including depression and suicide. Identification of individuals at risk of these sequelae can contribute to reducing the morbidity associated with acne.The Global Burden of Disease Project estimates the prevalence of acne at 9Á4%, ranking it as the eighth most prevalent disease worldwide. 1,2This initiative established prevalence and disability data from primary research manuscripts and databases, and conducted subsequent data analysis with a Bayesian meta-regression methodology, providing a means to harmonize discordant data and to account for a lack of data in geographical, temporal or other demographic items.2 While this project uses primary research findings to inform global metrics, there has not been a recent attempt to collate and present the world literature on acne prevalence collected over the past decade and a half. The last such review of acne prevalence in both general and schoolaged populations comprised literature up to 1995.

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“…Besides, the disorder is mostly seen as a physiological process rather than a medical problem, and its psychological effects on the individual can be ignored. On the other hand, AV has been shown to cause depression, anxiety, anger, fatigue, low self‐esteem, embarrassment, unhappiness with appearance, lowered self‐concept, self‐consciousness, decreased sexual activity, a decrease in school performance, and social withdrawal including multiple episodes of suicidal ideation in particularly the adolescent period …”

Section: Introductionmentioning

confidence: 99%