Psychological symptoms in anophthalmic patients wearing ocular prosthesis and related factors

Wang, Kai Jie; Li, Sha Sha; Wang, Hai Yan

doi:10.1097/md.0000000000021338

Cited by 15 publications

(10 citation statements)

References 24 publications

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“…However, the wearing/implantation of OP could cause a large amount of latent adverse effects on patients, among which the most frequently-reported symptoms include the increased tears and secretion, pain, burning sensation, etc. At present, these adverse symptoms are mostly attributed to the stimulation of ocular prosthesis to the conjunctival sac, poor installation, insufficient daily care of ocular prosthesis and allergy to ocular prosthesis materials ( Koch et al., 2016 ; Altin Ekin et al., 2020 ; Wang et al., 2020 ). To sum up, although the wearing of OP significantly contributes to patients’ aesthetic satisfaction, symptoms such as the increase of chronic secretions are often reported due to the heterogeneity of OP materials ( Pine et al., 2011 ).…”

Section: Introductionmentioning

confidence: 99%

Conjunctival sac microbiome in anophthalmic patients: Flora diversity and the impact of ocular prosthesis materials

Zhao

Chen

Zheng

et al. 2023

Front. Cell. Infect. Microbiol.

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PurposeTo explore the changes of bacterial flora in anophthalmic patients wearing ocular prosthesis (OP) and the microbiome diversity in conditions of different OP materials.MethodsA cross-sectional clinical study was conducted, involving 19 OP patients and 23 healthy subjects. Samples were collected from the upper, lower palpebral, caruncle, and fornix conjunctiva. 16S rRNA sequencing was applied to identify the bacterial flora in the samples. The eye comfort of each OP patient was determined by a questionnaire. In addition, demographics information of each participant was also collected.ResultsThe diversity and richness of ocular flora in OP patients were significantly higher than that in healthy subjects. The results of flora species analysis also indicated that in OP patients, pathogenic microorganisms such as Escherichia Shigella and Fusobacterium increased significantly, while the resident flora of Lactobacillus and Lactococcus decreased significantly. Within the self-comparison of OP patients, compared with Polymethyl Methacrylate (PMMA), prosthetic material of glass will lead to the increased colonization of opportunistic pathogens such as Alcaligenes, Dermabacter and Spirochaetes, while gender and age have no significant impact on ocular flora.ConclusionsThe ocular flora of OP patients was significantly different from that of healthy people. Abundant colonization of pathogenic microorganisms may have an important potential relationship with eye discomfort and eye diseases of OP patients. PMMA, as an artificial eye material, demonstrated potential advantages in reducing the colonization of opportunistic pathogens.

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Section: Introductionmentioning

confidence: 99%

Conjunctival sac microbiome in anophthalmic patients: Flora diversity and the impact of ocular prosthesis materials

Zhao

Chen

Zheng

et al. 2023

Front. Cell. Infect. Microbiol.

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“…[ 7 ] Anxiety and depression are more prevalent in patients with Leber hereditary optic neuropathy,[ 8 ] birdshot chorioretinopathy,[ 9 ] serpiginous choroiditis,[ 9 ] and in enucleated patients. [ 10 - 12 ]…”

Section: Introductionmentioning

confidence: 99%

Anxiety and Depression after Traumatic Open-Globe Injury

Hellman

Mahmood

Lin

2023

Journal of Emergencies, Trauma, and Shock

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Introduction: This cross-sectional interview-based study aimed to assess the prevalence and severity of probable anxiety and depression in patients with traumatic open-globe injury and to identify factors associated with anxiety and depression following open-globe injury. Methods: Two hundred and twenty-five patients with open-globe injury were identified at the UC Davis Medical Center between 2008 and 2019. Prisoners and patients under 18 at the time of recruitment were excluded from the study. One hundred and twenty-four patients provided consent to participate in the study, which involved a phone interview and chart review. The interview consisted of a section on sociodemographic data and potential associations followed by the Hospital Anxiety and Depression Scale, a standardized 14-question survey that has been validated in previous studies as an excellent predictor of anxiety and depression. A score of 8 for anxiety or depression was considered a positive test, and patients with a positive test in either category were advised to seek further evaluation with their primary care doctors. The prevalence of probable anxiety and depression was calculated, and linear regression was used to identify factors associated with anxiety and depression. Results: The average age was 50.5 ± 19.2, and 75.8% of patients were male. The anxiety score was positive in 37.9% of patients and the depression score was positive in 28.2%. The mean anxiety and depression scores were 6.3 ± 4.7 and 5.5 ± 4.8, respectively. The P value of the linear regressions for anxiety score and depression score were both < 0.001, with R 2 = 0.429 and 0.363, respectively. Younger age (P = 0.002) and unemployment at the time of the interview (P = 0.038) were associated with higher anxiety scores. Patients who were bothered by the appearance of their injured eye had higher anxiety scores (P < 0.001) and depression scores (P < 0.001). Patients without a high school diploma had higher depression scores (P < 0.001). Gender, enucleation status, number of people in support network, use of a prosthetic or scleral shell, final logMAR visual acuity, marital status, months since the initial injury, and presence of an intraocular foreign body were not significantly associated with anxiety or depression scores. Conclusions: Traumatic open-globe injury is associated with a high prevalence of probable anxiety and depression. Dissatisfaction with the appearance of the injured eye was associated with higher anxiety and depression scores. Younger age and unemployment were associated with increased anxiety scores, and lack of a high school diploma was associated with higher depression scores.

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“…Anophthalmic patients after enucleation not only have obvious functional deficits and facial deformities but also suffer from poor psychological outcomes [ 1 ]. Enucleation can result from complications, such as, for example, post-enucleation syndrome and phantom eye syndrome [ 2 ].…”

Section: Introductionmentioning

confidence: 99%

A Sandwich-Like Oral Mucosa Graft–Conjunctiva In Situ–Dermis-Fat Graft for Reconstruction of the Anophthalmic Socket with Ocular Infection History

et al. 2022

Ophthalmol Ther

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Introduction A novel technique of using a sandwich-like structure, namely, an oral mucosa graft (OMG)–conjunctiva in situ–dermis-fat graft (DFG) (OMG-C-DFG), to reconstruct a contracted and low-capacity anophthalmic socket for a patient with ocular infection history was evaluated. Methods This was retrospective case study of four patients (cases) who underwent anophthalmic socket reconstruction surgery in which the OMG-C-DFG technique was applied. The procedures were performed in the Department of Ophthalmology at the Ninth People’s Hospital, Shanghai JiaoTong University School of Medicine (Shanghai, China). Postoperative cosmetic appearance, graft outcome, the ability to wear an ocular prosthesis, and postoperative complications were evaluated. Results The median (± standard deviation) age of patients was 41.5 ± 22.1 (range 10–60) years. All patients suffered from contracted and low-capacity anophthalmic sockets. Three patients had a history of orbital implant infection and one patient had a history of enucleation due to exogenous endophthalmitis after globe rupture. The DFG and OMG were harvested from the abdominal region and lower lip, respectively. All four patients achieved a good postoperative appearance, with dermal surfaces appearing pink and smooth, the orbital areas showing good fullness, the ocular prosthesis showing good wearability, and no narrowing of the sockets. There was no lipid secretion, fat lysate outflow, or infection in the graft bed. There were only small amounts of scars and no infection of the donor site. Conclusion The sandwich-like structure can be effectively used to reconstruct the contracted and low-capacity anophthalmic socket with a history of orbital infection in one stage.

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Psychological symptoms in anophthalmic patients wearing ocular prosthesis and related factors

Cited by 15 publications

References 24 publications

Conjunctival sac microbiome in anophthalmic patients: Flora diversity and the impact of ocular prosthesis materials

Conjunctival sac microbiome in anophthalmic patients: Flora diversity and the impact of ocular prosthesis materials

Anxiety and Depression after Traumatic Open-Globe Injury

A Sandwich-Like Oral Mucosa Graft–Conjunctiva In Situ–Dermis-Fat Graft for Reconstruction of the Anophthalmic Socket with Ocular Infection History

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