“…Psychosocial factors have a significant impact on cancer patients' attitudes towards compliance with treatment, thereby causing refusal or discontinuation of treatment. These psychosocial factors included anxiety (Greer, Pirl, Park, Lynch, & Temel, 2008;Maric et al, 2010), depression, poor emotional and mental functioning (Maric et al, 2010), guilt and hostility (Ayres et al, 1994). A previous study revealed that distress and psychosocial needs (worry, fear, nervousness and sadness) are high in cancer patients at early stage, prior to chemotherapy (Mahendran, Lim, Chua, Lim, & Kua, 2015).…”