Psychological well‐being in patients with aneurysms‐osteoarthritis syndrome

Abstract

Aneurysms‐osteoarthritis syndrome (AOS) is characterized by arterial aneurysms and dissection in combination with early‐onset osteoarthritis, which can impact quality of life. We describe the subjective quality of life and investigate anxiety and depression in 28 AOS patients aged 15–73 years. Three questionnaires were used: 36‐Item Short Form Survey (SF‐36), hospital anxiety and depression scale (HADS) and Rotterdam disease specific questionnaire. Results of the SF‐36 and HADS were compared to a reference Dutch cohort and the SF‐36 questionnaire also to patients with Marfan syndrome. Compared to the general population, AOS patients scored significantly lower on the following SF‐36 domains: physical functioning, vitality, social functioning, bodily pain, and general health. Physical functioning was also lower than in Marfan patients. Patients with AOS scored higher on the HADS depression scale, while anxiety did not show a significant difference compared to the general population. No difference in SF‐36 and HADS domain scores were found between patient with and without orthopaedic symptoms and patients with or without previous aortic surgery. Additionally, we found that patients' worries for their future and heredity of their disease are important factors for anxiety, which should be addressed in clinical practice.

Health-related quality of life and lived experiences in males and females with thoracic aortic disease and their partners

“…Two are well-known validated questionnaires, the RDSQ questionnaire, however, was newly developed and used in one previous study so far. 10 Its psychometric properties have to be further evaluated. Therefore, results of this questionnaire are to be interpreted with caution.…”

“…The RDSQ for TAD was developed by a multidisciplinary team in our centre, including a cardiologist, psychologist, PhD candidate and physician assistant ( online supplemental file 1 ). 10 16 The purpose of this disease-specific questionnaire was to assess the impact of having TAD on daily life factors, such as: employment; family life; sexual functioning and sports participation. The questionnaire contains 18 statements which participants were asked to rate on a 10-point Likert scale.…”

“…In patients with HTAD, HRQOL was reduced as compared with the general population, and comparable to other chronic diseases. [7][8][9][10] To achieve HRQOL improvement, it is important to obtain more patient and disease-specific information on HRQOL and lived experiences. However, no studies to date have evaluated male-female-specific HRQOL in patients with TAD.…”