Two samples of university students, one from Turkey and the other from the USA, were compared on measures of attachment styles, difficulties in emotional regulation and self-reported symptoms of psychopathology. Results indicated that for both samples the level of anxiety in attachment and the lack of strategies in emotional regulation predicted several symptoms of psychopathology. Differences emerged in demographic predictors with parents' educational level predicting many of the symptoms in the Turkish population while age was the major demographic predictor in the USA sample. The results suggest that attachment and emotional regulation are universal personality factors contributing to psychopathology across cultures. The collectivistic cultural framework of the Turkish sample showed greater significance to family factors in contrast to the individualistic cultural influences in the USA sample.Keywords: attachment, emotional regulation, psychopathology, cross-cultural Psychopathology is multi-faceted and the determination of its predictors allows for early identification of symptoms, treatment, and prevention. Two major factors that have been related to psychopathology are the capacity for emotional regulation and attachment style (Dozier, Stovall-McClough, & Albus, 2008;Gross, 2014). Manifestations of psychopathology are characterized by disturbances in numerous processes (i.e., attention, cognition, behavior) including dysfunctional emotional processes which are impacted by, and contribute to, difficulties in regulating emotions (Kring, 2008). Insecure attachment styles, formed in childhood, set patterns of maladaptive strategies for maintaining relationships with others that involve the regulation of emotional distress (Dozier et al., 2008). The cross cultural examination between Turkish and USA university students in this current study considers the distinctions and similarities in how these factors predict symptoms of psychopathology across diverse cultural frameworks.In the last two decades, there has been increased attention to emotion regulation and its positive relation with mental health