Psychometric properties of the Chinese version of the FACT-L for measuring quality of life in patients with lung cancer

Wan, Chonghua; Zhang, Canzhen; Cai, Libai; Tu, Xin; Feng, Changyong; Luo, Jiahong; Zhang, Xiaoqin

doi:10.1016/j.lungcan.2007.01.004

Cited by 34 publications

(36 citation statements)

References 14 publications

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“…The QLICP-LU has several advantages over the Chinese versions of FACT-L and QLQ-LC43 although they have similar psychological properties [8,9]. First, it consists of a moderate number of variables with a clear hierarchical structure that can present mean scores computed not only at the domain levels but also at the different facet levels.…”

Section: Discussionmentioning

confidence: 99%

“…Eighty-four patients completed both the QLICP-LU and FACT-L and 82 patients completed both the QLICP-LU and QLQ-LC43 questionnaires, constituting the sample for the validation analysis of criterion-related validity. Correlation coefficients of scores among the domains of the QLICP-LU and FACT-L can be seen from a related article [8] and the ones among the domains of the QLICP-LU and multi-items subscales of QLQ-LC43 were presented in Table 4, with both showing that the correlations between the same and similar domains are generally higher than those between different and non-similar domains. For example, the coefficient between the psychological domain of QLICP-LU and emotional functioning of QLQ-LC43 was 0.67, higher than any other coefficients in this column, e.g., physical functioning (0.20), role functioning (0.24).…”

Section: Criterion Validitymentioning

confidence: 93%

“…The Chinese versions of FACT-L and QLQ-LC43 [8,9] were also used to provide data for assessing the criterion-related validity of the QLICP-LU. Psychometric properties of the instrument were subsequently analyzed.…”

Section: Evaluation Of the Qlicp-lumentioning

confidence: 99%

“…Although, the Chinese versions of QLQ-LC43 (QLQ-C30 and QLQ-LC13) and FACT-L can be used for Chinese patients [8,9], it is necessary to develop Chinese QOL instruments considering the cultural dependence of QOL. In Chinese culture, family relationship and kinship as well dietary culture play a very important role in personal and social life.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Development and validation of the system of quality of life instruments for cancer patients: Lung cancer (QLICP-LU)

Wan

Lu²,

Tang

et al. 2008

Lung Cancer

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Section: Discussionmentioning

confidence: 99%

Section: Criterion Validitymentioning

confidence: 93%

Section: Evaluation Of the Qlicp-lumentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Development and validation of the system of quality of life instruments for cancer patients: Lung cancer (QLICP-LU)

Wan

Lu²,

Tang

et al. 2008

Lung Cancer

Self Cite

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“…The FACT-L had been shown to be reliable and valid instruments to measure the QOL of Chinese lung cancer patients [22]. …”

Section: Methodsmentioning

confidence: 99%

The efficacy and roles of combining temozolomide with whole brain radiotherapy in protection neurocognitive function and improvement quality of life of non-small-cell lung cancer patients with brain metastases

et al. 2017

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BackgroundBrain metastasis (BM) is a poor prognostic factor for non-small-cell lung cancer (NSCLC). The efficacy and roles of combining temozolomide (TMZ) with whole brain radiotherapy (WBRT) in protection neurocognitive function (NCF) and improvement quality of life (QOL) were investigated and compared with WBRT alone in the treatment of NSCLC patients with BM.MethodsA total of 238 NSCLC patients with BM were reviewed and categorized into WBRT plus TMZ (RCT) arm and WBRT alone (RT), respectively. The efficacy was evaluated with Pearson chi-square or Fisher’s exact tests, Log-rank test and Cox proportional hazards model. NCF was assessed by using revised Hopkins Verbal Learning Test (HVLT-R), Controlled Oral Word Association (COWA) test and Trail-making Test (TMT). QOL was assessed by the Functional Assessment of Cancer Treatment-Lung (FACT-L) Chinese version 4.0 questionnaire.ResultsThe average intracranial objective response (ORR) and disease control rate (DCR) for all the patients were 26.9 and 95.8%, respectively. The intracranial ORR and DCR for RCT and RT arm were 34.9% vs. 20.2% (p = 0.01) and 98.4% vs. 92.7% (p = 0.03), respectively. The median intracranial progression-free survival (PFS) and overall survival (OS) of NSCLC patients with BM were 5.2 and 7.3 months, respectively. The median PFS of RCT arm was significantly longer than that of RT arm (5.9 vs. 4.9 months, p = 0.002). The median OS of the RCT arm was also slightly longer than that of the RT arm (8.5 vs. 5.9 months), but without statistical significance (p = 0.11). Multivariate analysis indicated that TMZ was a significant factor for PFS. Statistically significant differences on NCF and QOL were observed between CRT and RT arms at 5 months. RCT showed a trend of toxicities increase compared with RT, however, the toxicities were tolerable and manageable.ConclusionsAdding TMZ to WBRT in the treatment of NSCLC patients with BM could improve the intracranial ORR, DCR, and median PFS compared with WBRT alone. Although no remarkable difference on median OS was found, adding TMZ could prevent NCF and QOL from worsening. The side effects increased by adding TMZ, but the difference was not statistical significance and toxicities were well tolerated.

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The psychological distress of gastrointestinal cancer patients and its association with quality of life among different genders

Cheng,

Xie,

Duan

et al. 2024

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Background Psychological distress is a prevalent unpleasant experience faced by many cancer patients. However, the psychological distress among gastrointestinal (GI) cancer patients is scarcely explored. Moreover, the association between psychological distress and quality of life in different genders has yet to be explored. Aims To explore the psychological distress among GI cancer patients and examine its association with quality of life among different genders. Methods This study was a cross-sectional study. A total of 237 gastrointestinal cancer patients completed the distress thermometer and the Functional Assessment of Chronic Illness Therapy-General. Results The mean score of psychological distress of the participants was 3.04 (SD = 2.90). A greater proportion of female gastrointestinal cancer patients (52.8%) had clinically relevant psychological distress compared to males (35.9%). The quality of life was negatively associated with their psychological distress (B = − 1.502, 95%CI: − 2.759 to − 0.245, p = 0.019) among gastrointestinal cancer patients. Such association was stronger among males compared to females in gastrointestinal cancer patients (Interaction term, B = − 1.713, 95%CI: − 3.123 to − 0.303, p = 0.017). Conclusions These findings suggest that healthcare providers should attach their attention to gastrointestinal cancer patients’ psychological distress, especially females. Longitudinal studies could adopted to track the changes in psychological distress and its association with quality of life over time among different genders. In future intervention studies, the focus of psychological interventions needs to be gender-specific.

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Psychometric properties of the Chinese version of the FACT-L for measuring quality of life in patients with lung cancer

Cited by 34 publications

References 14 publications

Development and validation of the system of quality of life instruments for cancer patients: Lung cancer (QLICP-LU)

Development and validation of the system of quality of life instruments for cancer patients: Lung cancer (QLICP-LU)

The efficacy and roles of combining temozolomide with whole brain radiotherapy in protection neurocognitive function and improvement quality of life of non-small-cell lung cancer patients with brain metastases

The psychological distress of gastrointestinal cancer patients and its association with quality of life among different genders

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