Psychometrics of the chronic liver disease questionnaire for Southern Chinese patients with chronic hepatitis B virus infection

Abstract

AIM:To test the psychometric properties of a Chinese [(Hong Kong) HK] translation of the chronic liver disease questionnaire (CLDQ). METHODS:A Chinese (HK) translation of the CLDQ was developed by iterative translation and cognitive debriefing. It was then administered to 72 uncom plicated and 78 complicated chronic hepatitis B (CHB) patients in Hong Kong together with a structured questionnaire on service utilization, and the Chinese (HK) SF36 Health Survey Version 2 (SF36v2). RESULTS:Scaling success was ≥ 80% for all but three items. A new factor assessing sleep was found and items of two (Fatigue and Systemic Symptoms) subscales tended to load on the same factor. Internal consistency and testretest reliabilities ranged from 0.580.90 for different subscales. Construct validity was confirmed by the expected correlations between the SF36v2 Health Survey and CLDQ scores. Mean scores of CLDQ were significantly lower in complicated compared with uncomplicated CHB, supporting sensitivity in detecting differences between groups. CONCLUSION:The Chinese (HK) CLDQ is valid, reliable and sensitive for patients with CHB. Some modifi cations to the scaling structure might further improve its psychometric properties.

Validation of the Japanese version of the Chronic Liver Disease Questionnaire for the assessment of health‐related quality of life in patients with chronic viral hepatitis

“…Because most patients with CLD suffer from physical symptoms and/or worries which could greatly diminish their HRQOL and well‐being, it is crucial for physicians to appropriately evaluate and manage HRQOL problems of patients with CLD. For this purpose, the original CLDQ has been developed and validated, and its translated versions into other languages have been proved to be also reliable . In this report, we performed a validation study of the Japanese version of the CLDQ in Japanese patients with chronic viral hepatitis.…”

Evaluation of the quality of life people infected with HCV – proposed research instruments

“…The questionnaire contains 29 items divided into 6 groups concerning: the feeling of fatigue, life activity, emotional responses, abdominal complaints, general symptoms, and nervousness [9]. Another instrument is the Chronic Liver Disease Questionnaire -Hepatitis C (C systemic symptoms, and activity/energy.…”

Association between Hepatitis B-Related Knowledge and Health-Related Quality of Life

“…Existing literature reveals that patient with chronic diseases have poor HRQoL [3][4][5]. Within this context, Hepatitis-B (HB) affects more than 2 billion people worldwide, of these, 350 million have chronic, lifelong infection [6].…”

“…In addition, the advance stage development, expensive treatments and fear of death associated with HB sternly affects patients' daily life activities and results in decrease health status [8,9]. Moreover, HB causes loss of self-esteem, inability to function at work, anxiety, depression, and other emotional problems, hence resulting in poor HRQoL [3].…”