2022
DOI: 10.1016/j.brat.2022.104104
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Psychoneuroimmunology in the time of COVID-19: Why neuro-immune interactions matter for mental and physical health

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Cited by 21 publications
(8 citation statements)
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References 122 publications
(143 reference statements)
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“…The immunosuppressive state caused by the failure of T cells plays an improtant role in immune deficiency and the development of suboptimal health [ 1 , 2 ], as it not only strongly impairs the quantity and quality of lymphocytes but also has a pronounced impact on the generation of inflammatory cells and emotional well-being [ 32 , 33 ].…”
Section: Discussionmentioning
confidence: 99%
“…The immunosuppressive state caused by the failure of T cells plays an improtant role in immune deficiency and the development of suboptimal health [ 1 , 2 ], as it not only strongly impairs the quantity and quality of lymphocytes but also has a pronounced impact on the generation of inflammatory cells and emotional well-being [ 32 , 33 ].…”
Section: Discussionmentioning
confidence: 99%
“…This, in combination of the respiratory dysfunction experienced during both the acute phase of COVID-19 and the persistent sequelae, is likely to lead to cyclical breathing difficulties which may further exacerbate PTSS and, thus, fatigue. Bower et al [ 57 ] argue that both infection with SARS-CoV-2 and stressors encountered as a consequence of the pandemic may contribute to fatigue and psychiatric symptoms through overactivation of the proinflammatory cytokine network. They propose that distressing psychological states may increase inflammation, with an association between fatigue and elevated inflammatory markers noted in other health conditions.…”
Section: Discussionmentioning
confidence: 99%
“…Adequate sleep can boost immunity, as it allows the immune system to function optimally by promoting the production of immune cells and the release of cytokines that help defend the body against infections and diseases ( 27 ). Stress can potentially weaken innate and adaptive immunity to infections such as coronavirus disease 2019 (COVID-19), as chronic stress seems to suppress immune responses, making individuals more susceptible to infections, including the virus causing COVID-19 ( 28 , 29 ).…”
Section: Introductionmentioning
confidence: 99%