Psychopathological profile and quality of life of patients with oral lichen planus

Radwan-Oczko, Małgorzata; Zwyrtek, Edyta; Owczarek, Joanna Elżbieta; Szczęśniak, Dorota

doi:10.1590/1678-7757-2017-0146

Cited by 50 publications

(65 citation statements)

References 17 publications

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“…Several questionnaires were used in order to assess the impact of OLP on the patients' life quality. There was a positive correlation between the duration of the disease and the level of perceived stress and a negative correlation between the duration of the disease and the quality of life (16).…”

Section: Discussionmentioning

confidence: 92%

Photodynamic therapy as a new therapeutic approach of oral lichen planus

Tocut¹,

Mitran²,

Mitran³

et al. 2019

JMMS

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Oral lichen planus (OLP) is a chronic, immunologically mediated disease, defined by periods of exacerbation and quiescence. The disease is associated with a low mortality risk, but in some instances, morbidity can be important, especially in extensive, erosive forms, with a significant impact on the quality of life. OLP is a chronic T-cell mediated inflammatory disease involving the oral cavity, the most common lesions being located on the oral mucosa, tongue and gums. Its etiology remains in part unknown, but several factors proved to be involved in the development of the disease (drugs, dental materials, infectious agents, psychological factors, autoimmunity and genetic predisposition). The therapeutic approach should take into account the type of lesion and the extent of the disease, as well as the possible adverse effects. Although several therapies are available, OLP treatment still remains a challenge. Photodynamic therapy (PDT) is widely used in dermatology, finding applicability in the treatment of an increasing number of conditions. Recent research has shown the role of PDT in the treatment of OLP. It is a minimally invasive therapy with few side effects and promising results. Keywords  oral lichen planus, photosensitizer, therapy Highlights  The therapeutic approach in the OLP remains a challenge; although many therapies are available, none of them can still be considered the ideal therapeutic approach.  PDT seems to be a promising therapy, but with heterogeneous results due to lack of standardization (the available studies using different sources of light, wavelengths and photosensitizers).

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Section: Discussionmentioning

confidence: 92%

Photodynamic therapy as a new therapeutic approach of oral lichen planus

Tocut¹,

Mitran²,

Mitran³

et al. 2019

JMMS

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“…OLP has been classified as a premalignant lesion for its risk of malignant transformation (0.04-1.74 per year) in squamous cell carcinoma (OSCC) [56]. Patients affected by OLP suffer from burning and itching sensations up to a severe pain in the erosive form; the disease has a huge negative impact on quality of life due to impairment in daily activities such as eating or oral hygiene [57]. Published articles focused on salivary biomarkers in OLP are quite recent and concern the diagnosis of OLP, but in particular the early detection of malignant transformation.…”

Section: Oral Lichen Planusmentioning

confidence: 99%

Saliva and Oral Diseases

Martina

Campanati

Diotallevi

et al. 2020

JCM

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Saliva is a fascinating biological fluid which has all the features of a perfect diagnostic tool. In fact, its collection is rapid, simple, and noninvasive. Thanks to several transport mechanisms and its intimate contact with crevicular fluid, saliva contains hundreds of proteins deriving from plasma. Advances in analytical techniques have opened a new era-called "salivaomics"-that investigates the salivary proteome, transcriptome, microRNAs, metabolome, and microbiome. In recent years, researchers have tried to find salivary biomarkers for oral and systemic diseases with various protocols and technologies. The review aspires to provide an overall perspective of salivary biomarkers concerning oral diseases such as lichen planus, oral cancer, blistering diseases, and psoriasis. Saliva has proved to be a promising substrate for the early detection of oral diseases and the evaluation of therapeutic response. However, the wide variation in sampling, processing, and measuring of salivary elements still represents a limit for the application in clinical practice.

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“…From one point of view psychiatric disorders can have impact on exacerbation or acceleration of dermatological disease, and in other hand disorders, which are connected with the skin can be the reason of psychiatric illnesses [22]. Because of this and lack of well-known knowledge about etiopathogenesis of LP, it is consider to be psychosomatic illness [23]. Stress has impact on nervous system, both sympathetic and parasympathetic parts.…”

Section: Connection With Mental Diseasesmentioning

confidence: 99%

Current review of conections between lichen planus and mental disorders

Cholewa

Mitas

Zaremba

et al. 2020

J Educ Health Sport

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The major aim of this article was to examine causal connection or temporal relation between mental disorders and lichen planus (LP). LP is a chronic, inflammatory skin condition affecting less than 1% of the adult population. It is observed in many different clinical forms, some affecting more psychical state than others. Indeed, connection exist between LP and mental state. LP as an autoimmune disease can also be aggravated by psychosocial stressors. Etiopatogenesis of LP is idiopathic and involves immunologic components. Main pathogenetic mechanism of LP include increased apoptosis of keratinocytes and decreased apoptosis of T-cells. Many authors report relationship LP between mental illness like depression and anxiety disorder or lack of emotional stability. One of the main symptoms of LP is is severe itch (present in 74 from 78 patients), which can be induced by stress.

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Psychopathological profile and quality of life of patients with oral lichen planus

Cited by 50 publications

References 17 publications

Photodynamic therapy as a new therapeutic approach of oral lichen planus

Photodynamic therapy as a new therapeutic approach of oral lichen planus

Saliva and Oral Diseases

Current review of conections between lichen planus and mental disorders

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