Psychopathology, depression and dissociative experiences in patients with lichen simplex chronicus

Konuk, Numan; Koca, Rafet; Atik, Levent; Muhtar, Şennur; Atasoy, Nuray; Bostanci, Bora

doi:10.1016/j.genhosppsych.2007.01.006

Cited by 49 publications

(40 citation statements)

References 23 publications

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“…[1,2,6] According to Lynch, patients with LSC only rarely volunteer that psychological factors play a role in their disease. [1] Psychological factors have been shown to be associated with neurodermatitis in different studies by Shrivastava et al, [14] Ayyar and Bagadia, [15] Konuk et al, [16] and Singh et al [7] In our study, 31/105, (29.5%) patients admitted having some psychological factors playing a role in their disease causation and perpetuation. We found that 7 out of 105 patients (6.7%) were diagnosed to be suffering from psychiatric disorders.…”

Section: Discussionsupporting

confidence: 53%

Lichen simplex chronicus of anogenital region: A clinico-etiological study

Rajalakshmi

Thappa

Jaisankar

et al. 2011

Indian J Dermatol Venereol Leprol

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Section: Discussionsupporting

confidence: 53%

Lichen simplex chronicus of anogenital region: A clinico-etiological study

Rajalakshmi

Thappa

Jaisankar

et al. 2011

Indian J Dermatol Venereol Leprol

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“…Scores of the all tests were significantly higher in LSC group. 19 Radmanesh et al evaluated psychological status in 65 patients with psychogenic pruritus (including LSC, prurigo nodularis and neurotic excoriation) by a semistructured interview and concluded that all of them had affective disorders including depressions, anxieties, and mixed anxiety and depressive disorders. Some patients also had associated personality disorders, but no thought disorder was identified.…”

Section: Discussionmentioning

confidence: 99%

Psychological disorders in patients with lichen simplex chronicus: A comparative study with normal population

Goyonlo

Bordbar

Saadatian

et al. 2017

Polish Annals of Medicine

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Available online xxxKeywords: Lichen simplex chronicus Mental disorder Neurodermatitis a b s t r a c t Introduction: Lichen simplex chronicus (LSC) is an eczematous skin disease characterized by single or a few thickened and 'lichenified' skin plaques, with very disturbing itching. The role of psychological factors and transient relief of pruritus after violent scratching seems to be of great importance in development and perpetuation of its course. On the other hand, the chronic nuisance itching may lead to burdensome psychological distress and impaired quality of life. Aim: This study sought to elucidate more aspects of this interplay. Material and methods: 40 patients with LSC (diagnosed clinically) and 40 healthy controls (selected between attendants of the patients with no skin problem) were enrolled in this study. Hamilton questionnaire and symptom checklist 90-revised (SCL-90 R) were filled by a psychologist for all cases. Demographic characteristics, localization of the skin lesions, personal and family history of psychiatric disorders (if existent) were recorded.Results and discussion: Mean scores of SCL-90-R in somatization, interpersonal sensitivity, depression, anxiety, aggression, and phobia items were significantly higher in patient group than control group. Regarding Hamilton depression test, the mean scores were higher in patient group, but the difference was not statically significant.Conclusions: Patients with LSC are subject to ample psychiatric morbidities. Close collaboration of dermatologist and psychiatrist is essential in its successful control.

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“…Thus, LSC may be considered a form of NI [57]. Furthermore, an association between LSC and depression has been mentioned [58]. There is a high rate of depression in the elderly population [59].…”

Section: Neuropathic Itchmentioning

confidence: 99%

Chronic Pruritus in the Elderly: Pathophysiology, Diagnosis and Management

2015

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Chronic itch in the elderly is a common problem, with a significant impact on quality of life and sleep in elderly patients. Chronic itch may be attributable to several causes, including dry skin, immunosenescence and neural degeneration. Itch may also be caused by skin diseases, such as seborrhoeic dermatitis and stasis dermatitis; systemic conditions, such as end-stage renal disease and diabetes; and psychogenic conditions, such as depression and anxiety. The use of polypharmacy may also cause itch, with or without a rash. Specifically, thiazides and calcium channel blockers have been known to cause itch in elderly patients. Management should be tailored according to the underlying dermatological or systemic aetiology of itch. Topical treatment is the mainstay of therapy, providing special emphasis on skin hydration and barrier repair. In addition, topical and oral medications that target the nervous system and reduce neuronal hypersensitization, such as gabapentin and selective antidepressants, have a role in treating patients with severe chronic itch. Furthermore, management must account for changes in metabolism and pharmacokinetics of drugs in the aging population in order to prevent the occurrence of adverse effects.

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Psychopathology, depression and dissociative experiences in patients with lichen simplex chronicus

Cited by 49 publications

References 23 publications

Lichen simplex chronicus of anogenital region: A clinico-etiological study

Lichen simplex chronicus of anogenital region: A clinico-etiological study

Psychological disorders in patients with lichen simplex chronicus: A comparative study with normal population

Chronic Pruritus in the Elderly: Pathophysiology, Diagnosis and Management

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