Psychopathology profiles of acutely suicidal adolescents: Associations with post-discharge suicide attempts and rehospitalization

Berona, Johnny; Horwitz, Adam G.; Czyz, Ewa K.; King, Cheryl A.

doi:10.1016/j.jad.2016.10.036

Cited by 29 publications

(31 citation statements)

References 46 publications

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“…For other authors, the dysregulation profile may reflect a labile and reactive structure of psychopathology that is driven by difficulty regulating intense but transient aversive states [ 33 ].…”

Section: Discussionmentioning

confidence: 99%

High-school students and self-injurious thoughts and behaviours: clues of emotion dysregulation

et al. 2021

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Background Suicide attempts and self-harm in adolescence are a major public health concern: they are among the main causes of disability-adjusted life-years worldwide, with severe long-term health consequences in terms of mental illness and psychiatric hospitalisation and a significantly increased risk of suicide. Several studies recently focused on the hypothesis that adolescents may be particularly vulnerable to emotional dysregulation and on the relation between problems with emotion regulation and suicidal and self-harming behaviours. Italian epidemiological data about prevalence of these behaviours at the community level are lacking. Our study aimed to estimate the prevalence of self-injurious thoughts and behaviours (SITBs) in a representative sample of community adolescents, and to examine the association between SITBs and the emotional and behavioural profiles. Methods Anonymous self-report questionnaires were completed by 1507 students aged 11–18 years from 24 high schools in the North-eastern Italian region of Friuli Venezia Giulia. Information was collected on SITBs, on the socio-environmental context, and on the psychological profile (‘Achenbach’s YSR questionnaire 11–18, Multidimensional Test of Self-harm and Multi-Attitude Suicide Tendency Scale). Results Overall, 11.1% of adolescents reported self-harming behaviours without suicide ideation or attempts, 6.4% declared having thought to suicide without acting a suicide attempt or self-harm, 1.4% declared having attempted suicide and really thought to take away their life. Access to health services following a suicide thought, a self-harming behaviour or suicide attempt was infrequent, particularly for suicide ideation. At the YSR, all the SITBs groups reported high scores in almost all scales, with the most evident differences in the self-harming groups in which adolescents reported significantly higher scores in all scales, both internalising and externalising. An emotion dysregulation profile was found in almost all the groups. Conclusions This study provides us with an estimate of the prevalence of SITBs in the adolescent population and confirms the importance of further investigating the association between SITBs and emotion dysregulation. The naturalistic setting of community studies appears to be useful for studies in this field, and it allows to approach the onerous and often neglected issue of adolescent suicidality.

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Section: Discussionmentioning

confidence: 99%

High-school students and self-injurious thoughts and behaviours: clues of emotion dysregulation

et al. 2021

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“…However, we still lack quantitative comparisons of multiple dimensions of psychopathology across several SCAs [10]. Such approaches have proved fruitful in other clinical contexts (e.g., the CBCL-Dysregulation Pro le [CBCL-DP; [21,22]]; [23][24][25][26][27][28] -which strongly motivates pursuing their application in SCA research.…”

Section: Introductionmentioning

confidence: 99%

Patterns of Psychopathology and Cognition in Sex Chromosome Aneuploidy

Rau

Whitman

Schauder

et al. 2021

Preprint

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Background Sex chromosome aneuploidies (SCAs) are a collectively common family of genetic disorders that increase risk for neuropsychiatric and cognitive impairment. Beyond being important medical disorders in their own right, SCAs also offer a unique naturally-occurring model for X- and Y-chromosome influences on the human brain. However, it remains unclear if (i) different SCAs are associated with different profiles of psychopathology, and (ii) the notable interindividual variation in psychopathology is related to co-occurring variation in cognitive ability. Methods We examined scores for 11 dimensions of psychopathology [Child/Adult Behavior Checklist (CBCL)] and general cognitive ability [full-scale IQ (FSIQ) from Wechsler tests] in 110 youth with varying SCAs (XXY = 41, XYY = 22, XXX = 27, XXYY = 20) and 131 typically developing controls (XX = 59, XY = 72). Results All SCAs were associated with elevated CBCL scores across several dimensions of psychopathology, but social and attentional functioning were particularly sensitive to carriage of a supernumerary Y-chromosome. There was marked variability in CBCL scores within each SCA group, which generally correlated negatively with IQ, but most strongly so for social and attentional difficulties. These correlations showed subtle differences as a function of SCA group and CBCL scale. Conclusions There is domain-specific variation in psychopathology across SCA groups, and domain-specific correlation between psychopathology and IQ within SCAs. These findings (i) help to tailor clinical assessment of this common and impactful family of genetic disorders, and (ii) suggest that dosage abnormalities of X- and Y-linked genes impart somewhat distinct profiles of neuropsychiatric risk.

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“…NSSI is also associated with higher rates of suicidal ideation and behaviour, with approximately 70% of individuals with a history of NSSI attempting suicide at least once and 55% reporting multiple attempts (Asarnow et al ., 2011; Leibenluft, Gardner, & Cowdry, 1987; Nock, Joiner, Gordon, Lloyd‐Richardson, & Prinstein, 2006; Whitlock et al ., 2013). NSSI has been shown to be one of the strongest predictors of suicide attempts in individuals with mood disorders (Chesin et al ., 2017), and it increases the odds of re‐hospitalization by nearly two times among acutely suicidal adolescent inpatients (Berona, Horwitz, Czyz, & King, 2017).…”

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confidence: 99%

Understanding predictors of change in a day treatment setting for non‐suicidal self‐injury

2020

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Objectives. To examine change in non-suicidal self-injury (NSSI) frequency, quality of life, and functional impairment from admission to discharge in patients enrolled in partial hospitalization and intensive outpatient programmes (PHP/IOP) designed to treat NSSI. Demographic, clinical, and treatment-related predictors of changes were also examined.Design. Data were collected as part of routine clinical assessment procedures at admission and discharge from patients enrolled in a PHP/IOP programme designed to treat NSSI. The clinical assessment included measures examining quality of life, functional impairment, and NSSI behaviour.Methods. Paired t-tests were used to examine change in NSSI frequency, quality of life, and functional impairment. Reliable clinical change analyses were used to identify clinically significant change in quality of life and functional impairment. Multilevel mixed-effects regression was used to examine predictors of change for quality of life and functional impairment. Negative binomial regression was used to examine predictors of change for NSSI frequency.Results. From admission to discharge, NSSI frequency significantly decreased and quality of life and functional impairment evidenced clinically significant change. Age, race/ ethnicity, and insurance type predicted change in functional impairment, while gender predicted change in quality of life. Urge to self-injure predicted change in NSSI frequency. Borderline symptoms predicted change across all outcome variables. Conclusions.Patients who completed a day treatment programme for NSSI evidenced significant change in NSSI frequency, functional impairment, and quality of life at discharge; however, several demographic and clinical variables were associated with change. Practitioner pointsPatients who engage in NSSI show significant change from admission to discharge in a day treatment programme dedicated to the treatment of NSSI. Quality of life and functional impairment are important outcome variables to consider and evaluate in higher levels of care. It is important to consider demographic and clinical variables when creating a treatment plan for NSSI.

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Psychopathology profiles of acutely suicidal adolescents: Associations with post-discharge suicide attempts and rehospitalization

Cited by 29 publications

References 46 publications

High-school students and self-injurious thoughts and behaviours: clues of emotion dysregulation

High-school students and self-injurious thoughts and behaviours: clues of emotion dysregulation

Patterns of Psychopathology and Cognition in Sex Chromosome Aneuploidy

Understanding predictors of change in a day treatment setting for non‐suicidal self‐injury

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