Psychopharmacologic treatment of adolescent depression

Lynch, Arlene; Glod, Carol A.; Fitzgerald, Faye

doi:10.1053/apnu.2001.20580

Cited by 10 publications

(3 citation statements)

References 26 publications

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“…Two of the literature reviews addressed pharmacological treatment of depression in adolescents (Hamrin & Scahill, 2005;Lynch, Glod, & Fitzgerald, 2001). Although the reviewers found sufficient evidence to support moderate benefits of SSRIs, they pointed out that few randomized, controlled studies are available and that few studies examine the efficacy and effectiveness of newer antidepressants in children and adolescents.…”

Section: Results Of the Literature Reviewmentioning

confidence: 99%

“…This body of work also included the development of models to explain adolescent depression and the examination of depressive phenomena in both sexes. In addition, a few researchers have written extensive literature reviews that focus on cultural/ethnic groups of youth (e.g., Berrios, 2003;Choi et al, 2002;Siantz & Keltner, 2004) and psychopharmacologic treatment of depression in youth (Hamrin & Scahill, 2005;Lynch et al, 2001). This body of work also provides a guide to the identification and examination of culture and lifespan variables associated with depression in children and adolescents.…”

Section: Discussionmentioning

confidence: 99%

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The State of Nursing Science—cultural and Lifespan Issues in Depression: Part Ii: Focus on Children and Adolescents

Lutz

Warren

2007

Issues in Mental Health Nursing

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The manifestation of depressive phenomena is a complex, dynamic biopsychosocial process across cultures and the lifespan. Without appropriate treatment, depression persists and can have significant negative effects on the lives of youth, including an increased risk of suicide. Psychiatric mental-health (PMH) nurses are uniquely positioned to address this health concern. This manuscript is Part II of a review of current nursing literature on culture and lifespan aspects of depression. The review presented in Part II focuses on children and adolescents. This information can be used to enhance PMH nurses' knowledge of current nursing research and their efforts in addressing prevention, early intervention, education, and treatment of youth who experience depression.

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Section: Results Of the Literature Reviewmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

The State of Nursing Science—cultural and Lifespan Issues in Depression: Part Ii: Focus on Children and Adolescents

Lutz

Warren

2007

Issues in Mental Health Nursing

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“…However, not only adults suffer from depression: estimations of the prevalence of depression amongst adolescents range between 1% and 25% (Kessler et al, 2001;van Dulmen et al, 2002). Consequently, SSRIs are often prescribed to children and adolescents, despite a lack of demonstrated efficacy and safety data in this subgroup (Courtney, 2004;Lynch et al, 2001;Murray et al, 2004;Rushton et al, 2000). Besides the risk of side effects caused by SSRIs during treatment in adolescents (Wilnes et al, 2003), SSRIs might also disturb the development of the central nervous system that is still proceeding during adolescence (Spear, 2000).…”

Section: Introductionmentioning

confidence: 99%

Effects of chronic treatment with fluvoxamine and paroxetine during adolescence on serotonin-related behavior in adult male rats

Jong

Snaphaan

Pattij

et al. 2006

European Neuropsychopharmacology

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Selective Serotonin Reuptake Inhibitors (SSRIs) are designed to treat adults, but are increasingly prescribed for adolescents. SSRIs might cause permanent changes in serotonin-related behavior in adolescents, since their serotonergic system is still developing.Male Wistar rats were treated with paroxetine (15 mg/kg p.o.) or fluvoxamine (30 mg/kg p.o.) throughout adolescence. After a washout period their behavior in the elevated plusmaze, prepulse inhibition test, Forced swimming test and elevated T-maze were studied. In addition, the effects of the 5-HT 1A receptor agonist 8-OH-DPAT on sexual behavior and lower lip retraction were measured. Paroxetine mildly inhibited weight gain during treatment. Both SSRIs caused a reduction in ejaculation frequency and in time spent on the open arm of the elevated plus-maze in adult rats. avoidance latency in the elevated T-maze compared to paroxetine. No differences between the groups were found in the other tests. Apparently, chronic treatment with SSRIs during adolescence may cause mild changes in adult behavior.

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Current Awareness

2001

Human Psychopharmacology

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In order to keep subscribers up‐to‐date with the latest developments in their field, John Wiley & Sons are providing a current awareness service in each issue of the journal. The bibliography contains newly published material in the field of human psychopharmacology. Each bibliography is divided into 18 sections: 1 Books, Reviews & Symposia; 2 General; 3 Psychotropic Drugs ‐ General; Antidepressive Agents: 4 Tricyclics; 5 Monoamine Oxidase Inhibitors; 6 Serotonergics; Euthymic Agents: 7 Lithium; Tranquillizing Agents: 8 Major; 9 Minor & Hypnotics; 10 Analeptic Agents; 11 Anticonvulsant Agents; 12 Drugs of Abuse; 13 Transmitters, Receptors, Metabolites & Modulating Agents; 14 Neuropeptides; 15 Psychoneuroendocrinology; 16 Psychoneuroimmunology; 17 Behavioural Genetics; 18 Others. Within each section, articles are listed in alphabetical order with respect to author. If, in the preceding period, no publications are located relevant to any one of these headings, that section will be omitted.

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Psychopharmacologic treatment of adolescent depression

Cited by 10 publications

References 26 publications

The State of Nursing Science—cultural and Lifespan Issues in Depression: Part Ii: Focus on Children and Adolescents

The State of Nursing Science—cultural and Lifespan Issues in Depression: Part Ii: Focus on Children and Adolescents

Effects of chronic treatment with fluvoxamine and paroxetine during adolescence on serotonin-related behavior in adult male rats

Current Awareness

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