Psychosis Due to Quinidine Intoxication

Quintanilla, Jaime

doi:10.1176/ajp.113.11.1031

Cited by 5 publications

(2 citation statements)

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“…In contrast, a broader range of psychiatric effects specifically due to quinidine have been widely reported in the literature, including mood change [ 113 ], auditory hallucinations [ 114 , 115 ], visual hallucinations and delusions [ 115 , 116 ], paranoia [ 116 , 117 ], confusion, and delirium [ 116 , 118 ].…”

Section: Introductionmentioning

confidence: 99%

Psychiatric effects of malaria and anti-malarial drugs: historical and modern perspectives

Nevin

Croft

2016

Malar J

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The modern medical literature implicates malaria, and particularly the potentially fatal form of cerebral malaria, with a risk of neurocognitive impairment. Yet historically, even milder forms of malaria were associated in the literature with a broad range of psychiatric effects, including disorders of personality, mood, memory, attention, thought, and behaviour. In this article, the history of psychiatric effects attributed to malaria and post-malaria syndromes is reviewed, and insights from the historical practice of malariotherapy in contributing to understanding of these effects are considered. This review concludes with a discussion of the potentially confounding role of the adverse effects of anti-malarial drugs, particularly of the quinoline class, in the unique attribution of certain psychiatric effects to malaria, and of the need for a critical reevaluation of the literature in light of emerging evidence of the chronic nature of these adverse drug effects.

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Section: Introductionmentioning

confidence: 99%

Psychiatric effects of malaria and anti-malarial drugs: historical and modern perspectives

Nevin

Croft

2016

Malar J

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“…More recently, similar intoxicating effects from mefloquine, itself developed as a replacement for chloroquine , have become well characterized in the literature . Although the naturally occurring quinoline antimalarials have traditionally been considered free of such effects, cases of a related syndrome of intoxication have also occasionally been reported after relatively low doses of quinine and quinidine , suggesting a common intoxicating class effect.…”

Section: Introductionmentioning

confidence: 99%

Prolonged neuropsychiatric effects following management of chloroquine intoxication with psychotropic polypharmacy

Maxwell

Nevin

Stahl

et al. 2015

Clinical Case Reports

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Key Clinical MessageSusceptibility to quinoline antimalarial intoxication may reflect individual genetic and drug-induced variation in neuropharmacokinetics. In this report, we describe a case of chloroquine intoxication that appeared to be prolonged by subsequent use of multiple psychotropic medications. This case highlights important new considerations for the management of quinoline antimalarial intoxication.

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Properties of gap junction blockers and their behavioural, cognitive and electrophysiological effects: Animal and human studies

Juszczak¹,

Świergiel

2009

Progress in Neuro-Psychopharmacology and Biological Psychiatry

191

153

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Psychosis Due to Quinidine Intoxication

Cited by 5 publications

References 1 publication

Psychiatric effects of malaria and anti-malarial drugs: historical and modern perspectives

Psychiatric effects of malaria and anti-malarial drugs: historical and modern perspectives

Prolonged neuropsychiatric effects following management of chloroquine intoxication with psychotropic polypharmacy

Properties of gap junction blockers and their behavioural, cognitive and electrophysiological effects: Animal and human studies

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