“…At the same time, empirical studies have shown significant associations between PIU and PLEs in samples of young people [ 55 , 56 , 57 , 58 , 59 ], and the possible intersection between the diagnoses of hikikomori, PIU, and PLEs has recently been discussed [ 60 ]. Importantly, reports of clinical cases [ 61 , 62 , 63 , 64 , 65 , 66 , 67 , 68 , 69 ] have suggested that the excessive use of new technologies and PIU, when associated with social withdrawal, may constitute an important risk factor that is able to unmask psychotic vulnerability or foster the emergence of psychotic symptoms. The social deafferentation hypothesis of psychosis posits social isolation as a stressor which may trigger the development of psychotic experiences among individuals with pre-existing vulnerabilities [ 70 ].…”