Psychosocial Aspects of Genital Herpes: A Review of the Literature

Swanson, Janice M.; Chenitz, W. Carole

doi:10.1111/j.1525-1446.1990.tb00618.x

Cited by 18 publications

(7 citation statements)

References 42 publications

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“…12 The discrepancy may be partially explained by the frequency and severity of symptoms experienced by those with a clinical versus serological diagnosis of genital herpes. A clinical diagnosis of genital herpes is predicated upon a first episode of genital lesions, which may be a severe illness in a young, otherwise healthy person.…”

Section: Discussionmentioning

confidence: 99%

“…10 11 Conversely, opponents of screening believe that identifying those with mild or asymptomatic HSV-2 infection may result in the significant psychosocial sequelae associated with a clinical genital herpes diagnosis, outweighing the potential benefits of detection. [12][13][14] Among STD clinic attendees, adverse psychosocial outcomes associated with a serological diagnosis of genital herpes were modest. 15 16 In a recent qualitative study of 24 individuals, a new serological HSV-2 diagnosis was associated with strong psychosocial responses.…”

mentioning

confidence: 99%

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The psychosocial impact of serological herpes simplex type 2 testing in an urban HIV clinic

Meyer

2005

Sexually Transmitted Infections

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Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

The psychosocial impact of serological herpes simplex type 2 testing in an urban HIV clinic

Meyer

2005

Sexually Transmitted Infections

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“…While such therapy ameliorates the symptoms and lesions of HSV, the natural course of the disease is unaltered once antiviral therapy is stopped (2). In addition to the discomfort of the recurrent genital lesions, genital HSV is associated with stigma, which in many people is more burdensome than the clinical symptoms (3, 4). Such patients often request a curative intervention which would relieve them of the clinical disease as well as the need to disclose their status to sexual partners.…”

Section: Introductionmentioning

confidence: 99%

Attitudes and Willingness to Assume Risk of Experimental Therapy to Eradicate Genital Herpes Simplex Virus Infection

et al. 2016

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Background Current treatment of genital herpes is focused on ameliorating signs and symptoms but is not curative. However, as potential HSV cure approaches are tested in the laboratory, we aimed to assess the interest in such studies by persons with genital herpes, and the willingness to assume risks associated with experimental therapy. Methods We constructed an anonymous online questionnaire that was posted on websites that provide information regarding genital herpes. The questions collected demographic and clinical information on adults who self-reported as having genital herpes, and assessed attitudes toward and willingness to participate in HSV cure clinical research. Results 711 participants provided sufficient responses to be included in the analysis. 66% were women; the median age was 37 years, and the median time since genital HSV diagnosis was 4.7 years. The willingness to participate in trials increased from 59.0% in Phase 1 to 68.5% in Phase 2 and 81.2% in Phase 3 trials, and 40% reported willingness to participate even in the absence of immediate, personal benefits. The most desirable outcome was the elimination of risk for transmission to sex partner or neonate. The mean perceived severity of receiving a diagnosis of genital HSV-2 was 4.2 on a scale of 1 to 5. Conclusions Despite suppressive therapy available, persons with genital herpes are interested in participating in clinical research aimed at curing HSV, especially in more advanced stages of development.

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“…13 A survey that included 5000 herpes suVerers in the United States provided insight into the significant non-medical impact of herpes. 14 Over half the respondents reported feelings of depression and fear of rejection.…”

Section: Discussionmentioning

confidence: 99%

Impact of suppressive antiviral therapy on the health related quality of life of patients with recurrent genital herpes infection

Patel

Tyring

Strand

et al. 1999

Sexually Transmitted Infections

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Objective: To investigate whether suppressive antiviral therapy improves health related quality of life in patients with recurrent genital herpes. Methods: Health related quality of life was measured using the disease specific recurrent genital herpes quality of life questionnaire (RGHQoL) as part of a randomised, double blind, 52 week, placebo controlled, dose ranging study of once and twice daily valaciclovir or aciclovir for the suppression of recurrent genital herpes in patients with six or more recurrences per year. Results: Of 1479 participants, 1349 patients completed the baseline questionnaire. There were no significant baseline diVerences in RGHQoL score between any of the treatment groups. After 3 months there were significantly greater improvements in mean RGHQoL scores for all active treatment groups compared with placebo (p<0.05). Mean RGHQoL score improvements from baseline remained significantly higher in the active treatment groups than in the placebo group after 6 and 12 months, indicating that the improved health related quality of life in patients receiving suppressive antiviral therapy was sustained over a prolonged period of time. Conclusion: Suppressive antiviral therapy is an eVective strategy for improving the quality of life of patients with recurrent genital herpes. These improvements in quality of life are sustained over time, thus enhancing the clinical benefit in the long term management of this condition. (Sex Transm Inf 1999;75:398-402)

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Psychosocial Aspects of Genital Herpes: A Review of the Literature

Cited by 18 publications

References 42 publications

The psychosocial impact of serological herpes simplex type 2 testing in an urban HIV clinic

The psychosocial impact of serological herpes simplex type 2 testing in an urban HIV clinic

Attitudes and Willingness to Assume Risk of Experimental Therapy to Eradicate Genital Herpes Simplex Virus Infection

Impact of suppressive antiviral therapy on the health related quality of life of patients with recurrent genital herpes infection

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