Psychosocial aspects of the usage of modern technologies in diabetes mellitus

Мотовилин, Олег Геннадьевич; Геннадьевич, Мотовилин Олег; Суркова, Елена Викторовна; Викторовна, Суркова Елена; Baburyan, Anush S.; Самвеловна, Бабурян Ануш; Ибрагимова, Людмила Ибрагимовна; Ибрагимовна, Ибрагимова Людмила; Mayorov, Alexander Y.; Юрьевич, Майоров Александр

doi:10.14341/dm9972

Cited by 2 publications

(1 citation statement)

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As a result, diabetes is the most important medical and social problem on a global scale [ 4 ]. Currently, there is a need to develop programs for the active detection of diabetes during the early stages of the disease [ 5 , 6 ].…”

Section: Introductionmentioning

confidence: 99%

The intensity of free radical processes and chaperone activity in the saliva of patients with type 2 diabetes

Cheprasova¹,

Попов²,

Пашков³

et al. 2023

BioMedicine

View full text Add to dashboard Cite

Introduction Saliva is a clinically informative biological fluid that contains many biomarkers, allowing multiple analyses to be performed. Aim The objectives of this study were the assessment of the serum and saliva levels of biochemical parameters and intensity of free radical processes in T2DM patients and the identification of the correlation between certain criteria. Methods This case-control study included 40 T2DM patients, which were compared with 40 healthy individuals. The levels of glucose, cholesterol triglycerides, total protein, diene conjugates, and chaperone activity were measured using the spectrophotometric method. The concentration of 8-oxo-2′-deoxyguanosine was assessed by competitive enzyme-linked immunosorbent assay. Results It was established that the progression of diabetes led to an increase in glucose in saliva. The content of 8-oxo-2′-deoxyguanosine and conjugated dienes increased in serum and this increase was associated with the level of glucose and glycated hemoglobin. The level of protein and chaperone activity increased in the saliva of patients with T2DM compared with the control. The correlation analysis revealed a relationship between total protein concentration and conjugated dienes and between chaperone activity and conjugated dienes in saliva. Conclusions According to the results of the analysis, the pathological changes in DM affected the salivary glands and their secretions. The obtained results allowed us to recommend using saliva as an alternative to blood for the diagnosis and monitoring of T2DM treatments since it is readily available and quickly responds to changes in metabolism in the body.

show abstract

Section: Introductionmentioning

confidence: 99%

The intensity of free radical processes and chaperone activity in the saliva of patients with type 2 diabetes

Cheprasova¹,

Попов²,

Пашков³

et al. 2023

BioMedicine

View full text Add to dashboard Cite

show abstract

Central Part of the Auditory Analyser in Children with Type 1 Diabetes

Лазарева

Тарасенко

Черняк

2019

Kuban. nauсh. med. vestnik

View full text Add to dashboard Cite

Aim. The present article assesses the state of the central part of the auditory analyser in children with type 1 diabetes.Materials and methods. The study included 71 children with type 1 diabetes mellitus who were treated at the Endocrinology Department of the Children’s Territorial Clinical Hospital from September 2017 to February 2018. The children’s age ranged from 7 to 15 years (8±2.6). Group A comprised 34 children who were fi rst diagnosed with type 1 diabetes, with the duration of clinical manifestations not exceeding 3 months; whereas group B included 37 children who had been suffering from type 1 diabetes for 1–5 years. The control group was represented by 30 children of the same age group without a somatic pathology (group K). The functional state of the central part of the auditory analyser was assessed when studying brainstem evoked potentials of short, middle and long latency.Results. In the course of studying short-latency brainstem evoked potentials at a broadband-click stimulus frequency of 10 Hz and an intensity of 70 dB, the latent periods of peaks and peak-topeak intervals were analysed in groups A, B and K. Statistically signifi cant differences were observed for I and V latent periods of peaks, as well as for the I–V inter-peak interval. At a click stimulus intensity of 70 dB, peaks and peak-to-peak intervals of middle-latency brainstem evoked potentials revealed differences in the values of NO, PO, Na, Pa and NO–PO between the groups of patients with type 1 diabetes and the control group. Greater statistical differences, as compared to the control group, were observed in the latent periods of long-latency brainstem evoked potentials for interval P1 in group A and intervals P2 and N2 in group B (unfavourable course) during 100 dB stimulation at a repetition frequency of 1 Hz in a time window of 50 ms. The presence of differences between groups A and B in the parameters of peak P2 (p ≤ 0.07), as well as peak intervals P2–N2, N1–N2, N1–P1, N2–P2 and N1–P2, may indicate signifi cant differences in the centres of the auditory analyser (p ≤ 0.1). At the same time, the maximum activity of the studied parameters was found in the group of patients with newly diagnosed type 1 diabetes.Conclusions. The study of different types of brainstem evoked potentials, characterising the central parts of the auditory analyser, in children with type 1 diabetes allowed the authors to register functional disorders both in the brainstem segment and in the cortical structures. This fact indirectly indicates initial manifestations of diabetic neuropathy in the studied category of patients and can be used in the future for diagnosing CNS disorders.

show abstract

Psychosocial aspects of the usage of modern technologies in diabetes mellitus

Cited by 2 publications

References 27 publications

The intensity of free radical processes and chaperone activity in the saliva of patients with type 2 diabetes

The intensity of free radical processes and chaperone activity in the saliva of patients with type 2 diabetes

Central Part of the Auditory Analyser in Children with Type 1 Diabetes

Contact Info

Product

Resources

About