Psychosocial Distress Due to Interference of Normal Developmental Milestones in AYAs with Cancer

Itzep, Nelda; Roth, Michael

doi:10.3390/children9030309

Cited by 13 publications

(8 citation statements)

References 55 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…YAs endorsed, on average, 11 unmet needs, consistent with other studies reporting an average of 10-13 unmet needs. 6,23 Additionally, the most frequently endorsed concerns across sites align with existing literature reporting high levels of anxiety/fear, 26,27 concerns about bills/finances, 28,29 and concerns about social functioning/isolation. 27 A recent validation study used the AYA-POST 21 to measure distress and unmet needs in newly diagnosed YAs from Australia, Canada, the United Kingdom, and the United States.…”

Section: Discussionsupporting

confidence: 75%

Health Disparities in Young Adults: A Direct Comparison of Distress and Unmet Needs Across Cancer Centers

Markwardt,

Taghavi,

Shear

et al. 2024

JCO Clin Cancer Inform

View full text Add to dashboard Cite

PURPOSE Information on concerns that young adults (YAs) with cancer face when receiving care outside of specialized treatment centers is needed to increase equitable care to YAs at greater risk of marginalization by the health care system. The current study compared distress and unmet needs at the time of clinic visit between YAs receiving care from three different cancer clinics: (1) a National Cancer Institute–designated center, (2) a community-based clinic, and (3) a county hospital outpatient clinic. METHODS The Adolescent and Young Adult Psycho-Oncology Screening Tool (AYA-POST) was administered to measure distress and cancer-related concerns of YAs in active treatment. A one-way analysis of variance (ANOVA) compared distress scores by treatment site. A Fisher's exact test compared the number of participants endorsing each item on the Needs Assessment Checklist from each site. A simple linear regression determined the association between distress and number of items endorsed on the Needs Assessment Checklist. RESULTS Ninety-seven participants completed the AYA-POST, endorsing, on average, 11 concerns. Fisher's exact test showed significant differences between sites in the proportion of participants endorsing eight items: boredom ( P < .001), eating/appetite ( P < .001), nausea/vomiting ( P < .001), financial concern ( P = .002), hopelessness/helplessness ( P = .03), confidentiality ( P = .04), sibling concern ( P = .04), and insurance ( P = .05). The simple linear regression model was significant (F(1, 94) = 39.772, P < .001, R2 = 0.297), indicating the number of unmet needs accounted for almost 30% of the variance in distress. The one-way ANOVA was not significant (F(2, 93) = 1.34, P = .267). CONCLUSION Social determinants of health can influence the number and type of unmet needs experienced, affecting distress and other outcomes and underscoring the importance of timely, effective, age-appropriate screening and intervention for distress and unmet needs in YAs with cancer.

show abstract

Section: Discussionsupporting

confidence: 75%

Health Disparities in Young Adults: A Direct Comparison of Distress and Unmet Needs Across Cancer Centers

Markwardt,

Taghavi,

Shear

et al. 2024

JCO Clin Cancer Inform

View full text Add to dashboard Cite

show abstract

“…Cancer disrupts achievement of important life goals for many AYAs diagnosed with cancer. 39 for patients at high risk for poor physical and psychosocial health, with attention to patients from underserved communities.…”

Section: Foster Utilization Of Patient-reported Outcomes and Electron...mentioning

confidence: 99%

“…Cancer disrupts achievement of important life goals for many AYAs diagnosed with cancer 39 . Treatment‐related toxicity can impact patients’ health and HRQoL during and long after treatment.…”

Section: Strategic Approach: the Path Forwardmentioning

confidence: 99%

Children's Oncology Group 2023 blueprint for research: Adolescent and young adult oncology

Roth,

Grimes,

Reed

et al. 2023

Pediatric Blood & Cancer

View full text Add to dashboard Cite

Over the past few decades, 5‐year cancer survival has steadily improved for all adolescents and young adults (AYA, 15–39 years at diagnosis) combined. While encouraging, this progress simultaneously highlights a compelling need for improving survival in higher risk AYA subsets and for addressing health outcomes and health‐related quality of life (HRQoL) among long‐term survivors. The Children's Oncology Group (COG), in collaboration with the National Cancer Institute (NCI) and the adult network groups within the NCI National Clinical Trials Network (NCTN), has developed a large and growing portfolio of therapeutic AYA cancer clinical trials to identify optimal treatment approaches for common AYA cancers. Additional initiatives, led by the COG AYA Oncology Discipline Committee for increasing collaboration between the COG and the adult network groups, optimizing AYA clinical trial enrollment, and standardizing the assessment of HRQoL, have been highly successful to date. Further, NCTN‐wide collaborations are currently underway focused on improving survival for AYA malignancies with poor prognosis and, through development of supportive care and care delivery trials, reducing the short‐ and long‐term toxicity caused by cancer treatment. Leveraging the research infrastructure within the NCTN and the NCI Community Oncology Research Program, the COG will continue to champion meaningful advancements in health and survival for AYAs with cancer.

show abstract

“…[2][3][4] In developed countries, young adulthood is often when individuals complete formal education, launch careers, begin living independently, achieve financial independence, establish long-term emotional, romantic, and sexual relationships, and start families. 5,6 Core social relationships shift from being primarily with parents to including friends, colleagues, partners, and perhaps children. 5 However, YAs who have been diagnosed with cancer can experience delays in these sociodevelopmental milestones.…”

Section: Introductionmentioning

confidence: 99%

“…YAs with cancer face disease‐related and treatment‐related life disruptions that can negatively affect well‐being 2–4 . In developed countries, young adulthood is often when individuals complete formal education, launch careers, begin living independently, achieve financial independence, establish long‐term emotional, romantic, and sexual relationships, and start families 5,6 . Core social relationships shift from being primarily with parents to including friends, colleagues, partners, and perhaps children 5 .…”

mentioning

confidence: 99%

Social isolation and social connectedness among young adult cancer survivors: A systematic review

Fox,

Armstrong,

Gaumond

et al. 2023

Cancer

View full text Add to dashboard Cite

BackgroundSocial isolation and connectedness are social determinants of health that have demonstrated effects on cancer‐related outcomes. These constructs have been systematically evaluated among pediatric and older adult cancer populations. In this review, the authors evaluated the prevalence, correlates, and psychosocial implications of social isolation and connectedness among young adult (YA) cancer survivors aged 18–39 years.MethodsPeer‐reviewed articles published in English before June 2021 were identified from database searches and included articles' reference lists according to PRISMA (Preferred Reporting Items for Systematic Reviews and Meta‐Analyses) guidelines. Included articles described studies that assessed social isolation and/or connectedness among YA cancer survivors.ResultsIn total, 5094 unique records were identified; 4143 were excluded after title/abstract screening, and 907 were excluded after full‐text review. Forty‐four articles were included. Few studies used validated measures or directly assessed social isolation or connectedness. Social isolation was similarly prevalent among YAs and older cancer survivors and noncancer populations. Demographic, clinical, and behavioral risk and protective factors for social isolation were identified. Social isolation was related to worse psychological well‐being, whereas social connectedness was often, but not always, related to better psychological well‐being.ConclusionsThis growing literature underscores the relevance of social isolation and connectedness as important health determinants among YA cancer survivors. The identified risk and protective factors can identify YAs who especially may benefit from screening for social isolation. Future studies are needed that directly, reliably, and validly evaluate social isolation and connectedness to inform the development of interventions to decrease isolation and increase connectedness.

show abstract

Psychosocial Distress Due to Interference of Normal Developmental Milestones in AYAs with Cancer

Cited by 13 publications

References 55 publications

Health Disparities in Young Adults: A Direct Comparison of Distress and Unmet Needs Across Cancer Centers

Health Disparities in Young Adults: A Direct Comparison of Distress and Unmet Needs Across Cancer Centers

Children's Oncology Group 2023 blueprint for research: Adolescent and young adult oncology

Social isolation and social connectedness among young adult cancer survivors: A systematic review

Contact Info

Product

Resources

About