It was hypothesized that the relationship between maternal age and infant birthweight varies significantly across neighborhoods and that such variation can be predicted by neighborhood characteristics. We analyzed 229,613 singleton births of mothers aged 20-45 from Chicago, USA in 1997USA in -2002. Random coefficient models were used to estimate the between-neighborhood variation in age-birthweight slopes, and both intercepts-and-slopes-as-outcomes models were used to evaluate area-level predictors of such variation.The crude maternal age-birthweight slopes for neighborhoods ranged from a decrease of 17 grams to an increase of 10 grams per year of maternal age. Adjustment for individual-level covariates reduced but did not eliminate this between-neighborhood variation. Concentrated poverty was a significant neighborhood-level predictor of the age-birthweight slope, explaining 44.4 percent of the between-neighborhood variation in slopes. Neighborhoods of higher economic disadvantage showed a more negative age-birthweight slope. The findings support the hypothesis that the relationship between maternal age and birthweight varies between neighborhoods. Indicators of neighborhood disadvantage help to explain such differences. Keywords birth weight; maternal age; poverty; social environment; socioeconomic factors; multi-level modeling Low birthweight presents an important public health concern. Weight at birth is a good indicator of a mother's and an infant's nutritional status, as well as the newborn's chances for survival, growth, and long term health and psychosocial development. Studies have linked low birthweight to intellectual and cognitive delays (Boardman, Powers, Padilla, & Hummer, Corresponding Author: mcerda@umich.edu. Publisher's Disclaimer: This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final citable form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. The risk of low birthweight is unevenly distributed along social and economic lines, such as race and socioeconomic position. Infants of African-American women, for example, are twice as likely to be low birthweight as infants of White women (CDC, 2002). Much less investigated are the social disparities found in the risk of low birthweight associated with increasing maternal age. In this paper, we bring together research on the impact of urban neighborhoods on the health and development of residents with research on racial/ethnic and social disparities in health across the life course, to explore the systematic geographic patterning of the association between maternal age and birthweight.
NIH Public AccessNeighborhoods constitute a key determinant of racial and socioeconomic disparities in...