“…Previous studies have reported a short-term increase in psychological distress in women undergoing breast cancer screening [ 40 , 47 , 58 ]. However, in the current study, similar to other high-risk populations (e.g., individuals who carry a BRCA1 , BRCA2 or TP53 pathogenic variant, or with a family history of breast and pancreatic cancer) undertaking MRI-based cancer surveillance, stable or decreased measures of psychological distress were reported [ 39 , 48 , 59 , 60 ]. In this study, some women with NF1 did demonstrate higher levels of anxiety and cancer worry prior to breast cancer screening, compared to other MRI-based screening studies [ 39 , 40 , 48 , 59 , 60 ], which persisted over the course of the study.…”