Psychosocial interventions enhance HIV medication adherence: A systematic review and meta-analysis

Abstract

About 40 per cent of people living with HIV do not sufficiently adhere to their medication regimen, which adversely affects their health. The current meta-analysis investigated the effect of psychosocial interventions on medication adherence in people living with HIV. Databases were systematically searched, resulting in 43 included randomized controlled trials. Study and intervention characteristics were investigated as moderators. The overall effect size indicates a small to moderate positive effect (Hedges' g = 0.37) of psychosocial interventions on medication adherence in people living with HIV. No evidence for publication bias was found. This meta-analysis study concludes that various psychosocial interventions can improve medication adherence and thereby the health of people living with HIV.

Guided internet-based intervention for people with HIV and depressive symptoms: a randomised controlled trial in the Netherlands

“…1 A possible consequence of depression in PLWH is reduced adherence to antiretroviral therapy (ART). 2 Although several psychological interventions have been found to effectively reduce depressive symptoms, 3,4 improve ART adherence, 5 and quality of life, 3 many PLWH do not seek treatment when they feel depressed, due to, for example, perceived stigma. 6 Internet-based interventions may help to overcome barriers to depression treatment for PLWH.…”

Psychosocial Support Interventions for Improved Adherence and Retention in ART care for Young People Living with HIV (10-24 years): A Scoping Review

“…Interventions such as counselling, cognitive behavioural therapy, and peer support have been applied to improve the mental health and overall well-being of people living with HIV over 18 years with success [21], supporting the role of psychosocial support interventions in promoting adherence and retention in ART care among adults living with HIV [22]. Nevertheless, there is little evidence on the nature and role of psychosocial support for YPLHIV [23].…”

An Automated Intervention Did Not Improve Adherence to Oral Oncolytic Agents While Managing Symptoms: Results From a Two-Arm Randomized Controlled Trial

“…This finding differs from lower adherence rates to medications reported for other chronic conditions. 27,28 Moreover, it was in contrast with the higher nonadherence rates found in our pilot data, which were used to inform this trial. One possible explanation is that patients in the pilot study 21,22 were further into their course of treatment and could have been more likely not to adhere to their regimen compared with these patients who were initiating treatment.…”