Psychosocial Outcome of Children Evaluated for Short Stature

Zimet, Gregory D.; Owens, Ruth; Dahms, William T.; Cutler, Margaret G.; Litvene, Marilyn; Cuttler, Leona

doi:10.1001/archpedi.1997.02170470051010

Cited by 40 publications

(23 citation statements)

References 25 publications

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“…Short stature in MPS can be quite severe, frequently −3 to −6 standard deviations below the mean height for age and gender. Short stature this severe limits activities of daily living, and can negatively impact social development, socio-economic status, and career advancement [33,74,103]. This article will review the current published data on growth in children with MPS, and describe preliminary data on the potential use of human growth hormone (hGH) in children with MPS.…”

Section: Introductionmentioning

confidence: 99%

Growth patterns and the use of growth hormone in the mucopolysaccharidoses

Polgreen

Miller

2010

Journal of Pediatric Rehabilitation Medicine

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Short stature is characteristic of patients with mucopolysaccharidosis (MPS) diseases. For children with skeletal dysplasias, such as MPS, it is important to know the natural history of growth. An understanding of the natural growth pattern in each MPS disease provides a measurement to which treatments can be compared, as well as data which can help families and providers make individualized decisions about growth promoting treatments. Multiple advancements have been made in the treatment of MPS with both hematopoietic cell transplantation (HCT) and enzyme replacement therapy (ERT). The long term benefit of these treatments on growth is unknown. This article will review the published data on growth in children with MPS, and describe preliminary data on the use of human growth hormone (hGH) in children with MPS.

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Section: Introductionmentioning

confidence: 99%

Growth patterns and the use of growth hormone in the mucopolysaccharidoses

Polgreen

Miller

2010

Journal of Pediatric Rehabilitation Medicine

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“…Several studies have shown that short stature has minimal impact on psychological adaptation 27,28 , psychosocial functioning, and quality of life 29 of adolescents when compared to control groups.…”

Section: Discussionmentioning

confidence: 99%

Body Image in Adolescents with Disorders of Steroidogenesis

Cong

Green-Golan

Stratakis

et al. 2008

Journal of Pediatric Endocrinology and Metabolism

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Aim Little is known about body image in children with endocrine conditions. We evaluated body image in children with congenital adrenal hyperplasia (CAH), familial male precocious puberty (FMPP), and Cushing's syndrome (CS). Study design We compared 67 patients (41 CAH, 12 FMPP, 14 CS) age 8–18 years with 55 age-matched controls. Results Patients expressed more weight unhappiness than controls (females: p <0.001; males: p ~ 0.01). This difference remained for females after adjusting for body mass index (BMI) (p ~ 0.03), but not for males (p ~ 0.12). Unhappiness with height and age of appearance was similar between groups. In female patients, higher BMI was a significant predictor of weight unhappiness (p ~ 0.01). Conclusion Adolescents with CAH, FMPP, and CS are at risk for negative body image regarding weight, but not height or age of appearance. Weight unhappiness is partially related to greater weight, but factors unrelated to physical findings seem to contribute to negative body image in female patients.

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“…Other studies evaluating short normal children confirm that short stature can be a stressor. They found increased behavioral problems [23, 24]and emotional distress [25]among short-statured children. However, others came up with no differences in behavior or self-esteem [26].…”

Section: Discussionmentioning

confidence: 99%

Psychological Evaluation of Young Women after Medical Treatment for Central Precocious Puberty

et al. 2001

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Objective: This study aimed at the evaluation of the subjective experience and long-term behavioral and psychological effects of precocious puberty (PP). Methods: 19 female patients who had been treated with GnRH agonists participated in a semistructured interview and completed two standardized checklists. Their parents completed the Child Behavior Checklist (CBCL). Results: The CBCL yielded significantly elevated Internalizing and Total Behavior Problem scores. An elevated risk was found for patients with short adult stature and a relatively late onset of PP. The latter tended to neuroticism, to accentuation of their physical appearance, and felt significantly more insecure than age-related non-PP girls. Conclusion: Our findings suggest that PP can lead to specific behavioral problems, and that patients with a risk factor may need psychosocial support.

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Psychosocial Outcome of Children Evaluated for Short Stature

Cited by 40 publications

References 25 publications

Growth patterns and the use of growth hormone in the mucopolysaccharidoses

Growth patterns and the use of growth hormone in the mucopolysaccharidoses

Body Image in Adolescents with Disorders of Steroidogenesis

Psychological Evaluation of Young Women after Medical Treatment for Central Precocious Puberty

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