Psychosocial predictors of medication adherence among persons living with HIV

Gauchet, Aurélie; Tarquinio, Cyril; Fischer, Gustave Nicolas

doi:10.1007/bf03000185

Cited by 56 publications

(51 citation statements)

References 47 publications

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“…19 The findings in this study differ slightly to those of Gauchet et al, 34 who in their French study, examined the extent to which medication adherence in HIV patients related to social and psychological variables. Although the authors found patient beliefs about medicine to relate to adherence, as found in the current study, their findings showed that the influence of beliefs about medicine on medication adherence was also mediated by the patient-provider relationship and by HIV illness or medication representation on the part of the patients.…”

Section: Resultscontrasting

confidence: 61%

Self-efficacy, medication beliefs and adherence to antiretroviral therapy by patients attending a health facility in Pretoria

Adefolalu

Nkosi

Olorunju

et al. 2014

South African Family Practice

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Background: Self-efficacy and medication beliefs are known factors that influence adherence to treatment in chronic medical conditions. We carried out a cross-sectional study on human immunodeficiency virus (HIV)-infected patients with the aim of determining the predictive relationship between these two variables and adherence to antiretroviral therapy (ART) at a health facility in Pretoria. Method: Participants' medication beliefs were assessed using the Beliefs about Medicines Questionnaire. Self-efficacy was evaluated using the HIV Adherence Self-Efficacy Scale, and adherence to ART determined using the AIDS Clinical Trial Group questionnaire. Results:The mean age of the 232 participants was 40 years (standard deviation 15.6). Seventy per cent were females. Most had been on ART for over two years (87%), and 81.5% were adherent to at least 95% of the prescribed antiretroviral drugs. Nonadherence was highest in those on ART for more than three years (63%). The mean HIV Adherence Self-Efficacy score was 6.45 out of a possible 10. Beliefs held by the participants about the importance of (necessity) and concerns about ART in the management of HIV infection were generally positive. There was a mean score of 4.05 out of 5, indicating a strong belief in the use of ART. There was a strong association between adherence self-efficacy and ART adherence (p < 0.001) in the nonadherent participants. Regression analysis showed significance for adherence self-efficacy on ART nonadherence (p < 0.041), with adherence self-efficacy explaining 9.8% of the variance. Conclusion: Patients' adherence self-efficacy explained a significant portion of variation in the nonadherence to ART, which suggests that low adherence self-efficacy is influential in ART nonadherence. Interventions aimed at improving adherence to ART should address adherence self-efficacy.

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Section: Resultscontrasting

confidence: 61%

Self-efficacy, medication beliefs and adherence to antiretroviral therapy by patients attending a health facility in Pretoria

Adefolalu

Nkosi

Olorunju

et al. 2014

South African Family Practice

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“…Of the papers relating beliefs about medicines to a measure of medication adherence, some report only necessity beliefs are correlated to medication adherence [19,21,22,[35][36][37][38] while others have found only concern beliefs to be correlated to medication adherence [30,[39][40][41][42][43]. In some studies, the necessity-concerns differential was shown to have a stronger correlation with adherence than necessity or concern beliefs alone [4,20,44,45].…”

Section: Introductionmentioning

confidence: 99%

The necessity–concerns framework predicts adherence to medication in multiple illness conditions: A meta-analysis

Foot

Caze

Gujral

et al. 2016

Patient Education and Counseling

139

104

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2 Highlights We investigated the relationship between medication beliefs and adherence  Necessity beliefs were significantly positively correlated with adherence  Concern beliefs were significantly negatively correlated with adherence  Necessity effect size was different in asthma and cardiovascular group 3 Abstract ObjectiveThis meta-analysis investigated whether beliefs in the necessity and concerns of medicine and the necessity-concerns differential are correlated with medication adherence on a population level and in different conditions. MethodsAn electronic search of Web of Science, EMBASE, PubMed and CINAHL was conducted for manuscripts utilising the Beliefs about Medicines Questionnaire and comparing it to any measure of medication adherence. Studies were pooled using the random-effects model to produce a mean overall effect size correlation. Studies were stratified for condition, adherence measure, power and study design. ResultsNinety-four papers were included in the meta-analysis. The overall effect size(r) for necessity, concerns, and necessity-concerns differential was 0.17, -0.18 and 0.24 respectively and these were all significant (p<0.0001). Effect size for necessity was stronger in asthma and weaker in the cardiovascular group compared to the overall effect size. ConclusionNecessity and concerns beliefs and the necessity-concerns differential were correlated with medication adherence on a population level and across the majority of included conditions. The effect sizes were mostly small with a magnitude comparable to other predictors of adherence. Practice implicationsThis meta-analysis suggests that necessity and concern beliefs about medicines are one important factor to consider when understanding reasons for non-adherence.

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“…However other researchers argue that long waiting times, poor staff attitudes, intermittent drug availability and other procedural barriers decrease patients' adherence to ART and also result in poor clinic attendance [19][20]. Continuous accessement to health care services and medications by patients also influences treatment adherence [19].…”

mentioning

confidence: 99%

“…Continuous accessement to health care services and medications by patients also influences treatment adherence [19]. The patient-provider relationship as emphasized by Altice et al [16] and Gauchet et al in their studies, is another factor that has been well researched in terms of adherence to ART [20]. The same authors continue to state that a good patient-provider relationship results in patient's trust and confidence in the provider which in turn influences good adherence [16,20].…”

mentioning

confidence: 99%

An Assessment of the Level of Knowledge of HIV-Infected Patients about Highly Active Antireteroviral Therapy and Waiting Times and Their Influence on Antiretroviral Therapy Adherence at a Primary Healthcare Centre of South Africa

Katende-Kyenda¹,

Apalata²

2017

JPP

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Abstract:Objectives: The study assessed if the level of knowledge of HIV-infected about HAART and waiting-times in the PHC (primary healthcare) clinic have an influence on antiretroviral adherence. Methods: A descriptive-cross-sectional study was conducted in South Africa. Data collected uses a standardized-questionnaire and face-to-face-exit interviews. Pill-count technique was performed and a value of ≥ 95% acceptable. Data were analysed using SPSS. Univariate-factors associated with poor-adherence to knowledge about HAART and waiting times were assessed using ANOVA and p ≤ 0.05 considered statistically significant. Key findings: Of 86 enrolled, 63(73.3%) were females and 23(26.7%) males, with mean-age (± SD) of 35.6(±9.6) years and on HAART for 35.5(± 31.8) months ranging from 1-137. Of these, 27(31.40%) and 25(29.07%) were on WHO stages 2 and 3 respectively. Adherence-rates computed from 32 patients, 23(71.9%) revealed poor adherence-rates. The level of knowledge about HAART in terms of names of tablets, correct-dose, frequency, adverse-effects had no influence on ARV-adherence (p ≥ 0.05). Of 23 non-compliant, 10 (40%) gave the reason of drugs-unavailability, 7(30%) adverse-effects, 5(20%) drugs' complexity, and 1(10%) too busy to take them. Waiting areas associated with poor ARV-adherence were reception (p = 0.028), doctors (p = 0.027), while nurse's station (p = 0.29) and pharmacy (p = 0.43) revealed acceptable ARV-adherence.

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Psychosocial predictors of medication adherence among persons living with HIV

Abstract: The data suggest that patients' beliefs about treatment are formed to a certain degree in the patients' relationship with the physician. Furthermore, adherence seems to be related to personal values.

Cited by 56 publications

References 47 publications

Self-efficacy, medication beliefs and adherence to antiretroviral therapy by patients attending a health facility in Pretoria

Self-efficacy, medication beliefs and adherence to antiretroviral therapy by patients attending a health facility in Pretoria

The necessity–concerns framework predicts adherence to medication in multiple illness conditions: A meta-analysis

An Assessment of the Level of Knowledge of HIV-Infected Patients about Highly Active Antireteroviral Therapy and Waiting Times and Their Influence on Antiretroviral Therapy Adherence at a Primary Healthcare Centre of South Africa

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