Oocyte donations are ethical, social, religious, physiological, and medical problems. The medical risks of oocyte donation are not adequately addressed. The risks of oocyte donation require careful examination of the treatment of oocyte donors during the donation process. There are some long-term risks and various side effects such as pain, infection, oocyte retention, bleeding, premenstrual syndrome-like symptoms, ovarian hyperstimulation syndrome (OHSS), and the risk of ovarian cancer related to the drugs used by the donor. Treatment with oocyte donation is one of the situations in which the most common methods of assisted reproduction are discussed. There are many differences in moral, ethical, and religious issues in society. The use of donor eggs, sperm, or embryos is a social or cultural problem rather than a medical problem. For this reason, legal regulations on oocyte donation are carried out in line with cultural beliefs and public opinion about the procedure; individuals are free to use legal procedures according to their values. However, the fact that it is prohibited in some communities can push the illegal paths by obstructing the ones who want to use it.