Psychosocial support interventions to improve treatment outcomes for people living with tuberculosis: a mixed methods systematic review and meta-analysis

Maynard, Claire; Tariq, Shema; Sotgiu, Giovanni; Migliori, Giovanni Battista; Boom, Martin van den; Field, Nigel

doi:10.1016/j.eclinm.2023.102057

Cited by 6 publications

(1 citation statement)

References 48 publications

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“…There is a strong desire among them to identify and use all the coping resources they have amidst the psychological burden they feel as a result of suffering from tuberculosis, and this is a very interesting finding to discuss. This finding is very relevant to their efforts to find a way out of their misery so that they can survive sporadic mental attacks [ 96 , 97 ], and this is obtained when their psychological environment can explore personal resources and environmental resources to free themselves from feelings of depression [ 98 – 100 ], and a religious spiritual approach is the most ideal approach [ 101 , 102 ] as also reported in this research. Therefore, they have a sense of self-confidence and physical strength that makes them feel protected, fulfilled, and satisfied [ 88 , 103 ].…”

Section: Discussionmentioning

confidence: 72%

Coping efforts made: Psychological burden of people living with tuberculosis due to social stigma in society. A qualitative phenomenology study

Nasir,

Hassan,

Ma’ruf

et al. 2024

PLoS ONE

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The psychological burden is greatly felt by people living with tuberculosis because the characteristics of the disease are very visible and very contagious, and the obligation to take the right dose of medication with long treatment. This is what makes tuberculosis a very stigmatic disease. The aim of this research is to explore the psychological burden felt by people living with tuberculosis due to social stigma by society and how coping efforts are made. This research uses a qualitative phenomenological design through in-depth face-to-face interviews which take place in a semi-structured manner with the hope of obtaining complete data. The purposive sampling method was used in this research with Participatory Interpretative Phenomenology analysis involving 25 participants consisting of 16 men and 9 women. This research produced several themes, including 1) "The Perception of stigma limiting space and time", 2) "The Opportunities for interpersonal interaction become narrow", 3) "The mental stress as a challenging emotion", and 4) " Expanding coping efforts”. The psychological burden is felt by people living with tuberculosis because society’s treatment is felt to be very discriminatory due to the social stigma that has developed in society so they lose the opportunity to interact with society. For that reason, they tried to explore some of the personal and environmental resources used to modify adaptive coping in resolving perceived psychological burdens. Given the possibility of ongoing stigma and discrimination during tuberculosis treatment programs, it is important to consider the psychological burden in this context, both on the general population and on groups affected by stigma.

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Section: Discussionmentioning

confidence: 72%

Coping efforts made: Psychological burden of people living with tuberculosis due to social stigma in society. A qualitative phenomenology study

Nasir,

Hassan,

Ma’ruf

et al. 2024

PLoS ONE

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RETRACTED ARTICLE: How does environmental performance ensured energy transition? Impact of ecological change

Liu,

Zhang

2024

Econ Change Restruct

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Mortality and lost to follow-up among Tuberculosis patients on treatment in Meru County, Kenya: a retrospective cohort study

Ngari,

Mberia,

Kanana

et al. 2024

Preprint

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Tuberculosis (TB) remains a leading cause of death globally. Patients who get lost-to-follow-up (LTFU) during TB treatment have high risk of relapse, mortality, treatment failure and developing Multidrug resistant TB. Empirical data to monitor long-term TB treatment outcomes in low-and-middle income countries (LMICs) are sparse. We determined proportion of TB patients who die or are LTFU during six months of treatment and identified factors independently associated with mortality or LTFU. A retrospective cohort using data from routine Meru County TB surveillance system. We included 38020 records of TB patients aged ≥15 years on treatment 2012 to 2022. TB treatment outcomes of interest were LTFU or death within six months of treatment. Survival analyses accounting for competing events were performed. Among the 38020 patients included, 27608 (73%) were male and the median (IQR) age was 32 [25-42] years. 26599 (70%) had bacteriologically confirmed TB while 11421 (30%) were clinically diagnosed. During 16531 person-years of follow-up, 2385 (6.3%, 95%CI 6.0-6.5) and 1942 (5.1%, 95%CI 4.9-5.3) patients were LTFU and died respectively. In the multivariable model, patients on re-treatment after LTFU or after failure and those previously treated compared to new TB patients were positively associated with LTFU. Patients coinfected with HIV and those with unknown HIV status were positively associated with LTFU. In contrast, females, clinically diagnosed, extra-pulmonary TB and older patients were negatively associated with LTFU. Patients HIV infected on ARVs, not on ARVs and unknown HIV status versus not infected were positively associated with mortality. Other comorbidities (not HIV), clinically diagnosed, undernourished and older patients were positively associated with mortality. More than 10% of TB patients either die or are LTFU before completing treatment. TB patients on re-treatment, HIV infected, clinically diagnosed, undernourished and the elderly needs more targeted interventions to improve survival and successfully treatment.

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Psychosocial support interventions to improve treatment outcomes for people living with tuberculosis: a mixed methods systematic review and meta-analysis

Cited by 6 publications

References 48 publications

Coping efforts made: Psychological burden of people living with tuberculosis due to social stigma in society. A qualitative phenomenology study

Coping efforts made: Psychological burden of people living with tuberculosis due to social stigma in society. A qualitative phenomenology study

RETRACTED ARTICLE: How does environmental performance ensured energy transition? Impact of ecological change

Mortality and lost to follow-up among Tuberculosis patients on treatment in Meru County, Kenya: a retrospective cohort study

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