Psychosomatic Factors in Dermatology

Urpe, Mauro; Pallanti, Stefano; Lotti, Torello

doi:10.1016/j.det.2005.05.021

Cited by 23 publications

(23 citation statements)

References 55 publications

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“…4,7,8 LSC is one of the most common prototypes of psychocutaneous disorders, its behavioral and psychological aspects and its impact on quality of life of the patient has been widely reviewed in different populations. [9][10][11] There are reports that associate it with affective disorders, and consider serotonin as the principal linking mediator, whose metabolism is changed in the skin of LSC patients. 12 Also, another controlled study supports higher rates of depression among LSC patients in different populations.…”

Section: Introductionmentioning

confidence: 99%

Psychological disorders in patients with lichen simplex chronicus: A comparative study with normal population

Goyonlo

Bordbar

Saadatian

et al. 2017

Polish Annals of Medicine

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Available online xxxKeywords: Lichen simplex chronicus Mental disorder Neurodermatitis a b s t r a c t Introduction: Lichen simplex chronicus (LSC) is an eczematous skin disease characterized by single or a few thickened and 'lichenified' skin plaques, with very disturbing itching. The role of psychological factors and transient relief of pruritus after violent scratching seems to be of great importance in development and perpetuation of its course. On the other hand, the chronic nuisance itching may lead to burdensome psychological distress and impaired quality of life. Aim: This study sought to elucidate more aspects of this interplay. Material and methods: 40 patients with LSC (diagnosed clinically) and 40 healthy controls (selected between attendants of the patients with no skin problem) were enrolled in this study. Hamilton questionnaire and symptom checklist 90-revised (SCL-90 R) were filled by a psychologist for all cases. Demographic characteristics, localization of the skin lesions, personal and family history of psychiatric disorders (if existent) were recorded.Results and discussion: Mean scores of SCL-90-R in somatization, interpersonal sensitivity, depression, anxiety, aggression, and phobia items were significantly higher in patient group than control group. Regarding Hamilton depression test, the mean scores were higher in patient group, but the difference was not statically significant.Conclusions: Patients with LSC are subject to ample psychiatric morbidities. Close collaboration of dermatologist and psychiatrist is essential in its successful control.

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Section: Introductionmentioning

confidence: 99%

Psychological disorders in patients with lichen simplex chronicus: A comparative study with normal population

Goyonlo

Bordbar

Saadatian

et al. 2017

Polish Annals of Medicine

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“…A recent study involving a mouse model of inflammation demonstrated that MMF inhibits the production of various proinflammatory cytokines [9]. Specifically, MMF was found to inhibit both the synthesis and release of IFN-α, IL-1b, VEGF-α and IL-17 from activated leuko cytes [9]. Similarly, the antipruritic effect of MMF on our patient may be attributed to its role in suppressing inflammatory cascades such as those responsible for the disease processes of prurigo and LCS.…”

Section: Discussionmentioning

confidence: 72%

“…Therefore, a plausible hypothesis for the effectiveness of MMF in neurodermatitis may lie in the attenuation of immune responses secondary to psychogenic factors. A recent study involving a mouse model of inflammation demonstrated that MMF inhibits the production of various proinflammatory cytokines [9]. Specifically, MMF was found to inhibit both the synthesis and release of IFN-α, IL-1b, VEGF-α and IL-17 from activated leuko cytes [9].…”

Section: Discussionmentioning

confidence: 99%

Therapeutic prospects of mycophenolate mofetil for the treatment of neurodermatitis

Reddy

Jow

Hantash

2013

Expert Review of Dermatology

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“…We emphasize the necessity of the presence of psychodermatology as a working discipline from different standpoints and assess its situation in the future as a subspecialty. [4][5][6][7] . Doktor hasta iliflkisi ele al›nd›¤›nda ilk ad›m iyi iletiflim becerilerinin elde edilmesidir.…”

Section: Discussionmentioning

confidence: 99%

The Future of Psychodermatology

Altunay¹

2010

turkderm

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‹lknur K›vanç Altunay fiiflli Etfal E¤itim ve Araflt›rma Hastanesi, Dermatoloji Klini¤i, ‹stanbul, Türkiye 55 GiriflVücudun ve ruhun örtüsü olarak deri d›fl dünya ile kiflinin iç evreni aras›ndaki en önemli iletiflim arac› ve en önemli duyu olan dokunsal alg›lar›n kayna¤›d›r. Kiflileraras› iliflkilerde ve cinsel kimlikle ilintili olarak kendilik alg›s› ve beden imaj› oluflturulmas›nda yaflamsal önemi vard›r. Bunun sonucu olarak deri hastal›¤› olan kiflilerin görünümlerinin ve hareketlerinin toplum içindeki tepkilere duyarl› olmas› kaç›n›lmaz bir sonuç olarak ortaya ç›kmaktad›r. Deri hastal›¤›n›n di¤er baflka hastal›klar-dan en önemli fark› onun görünür olma özelli¤idir. Dolay›s›yla deri hastas› kendisi hakk›nda oldukça negatif, önyarg›l› ve ayn› zamanda damgalanm›fl gibi hissetmektedir. Gerçekte de toplumdaki ço¤u kiflinin deri hastalar›na farkl› bir gözle bakmalar› ve bir tür reddetme davran›fl› içine girmeleri mümkündür. Bu noktada zedelenen özgüven ve beden alg›s›n›n düzeltilmesi bazen deri hastal›¤›n›n düzeltilmesinden çok daha fazla ön plana geçmektedir 1-4 . Son y›llarda bireyin görselli¤ine hizmet eden estetik cerrahi, moda, diyet alanlar›nda önemli ölçüde geliflmeler olmufl ve bu alanlardaki uygulamalar oldukça büyük ölçekli parasal yat›r›mlarla ifllerlik ve önem kazanm›flt›r. Özellikle bat› dünyas›nda kozmetik ve reklam endüstrisi çekici insanlar›n mutlu, baflar›l› ve sevgiye de¤er olduklar› temas›n› beyinlere ve ruhlara enjekte ederek kiflilerin fiziksel görünümlerinde eriflimi zor olan standartlara ulaflmalar› için ola¤anüstü bir bask› yaratmaktad›r. Bu koflullarda görünür bir hastal›¤›n kiflilerde yol açabilece¤i psikososyal sonuçlar›n beklenenden daha çok olmas› olas›d›r. Derideki flekil Y Ya az z› ›fl flm ma a A Ad dr re es si i/ /A Ad dd dr re es ss s f fo or r C Co or rr re es sp po on nd de en nc ce e: : Dr. ‹lknur K›vanç Altunay, fiiflli Etfal E¤itim ve Araflt›rma Hastanesi, Dermatoloji Klini¤i, ‹stanbul, Türkiye E-posta: ialtunay@gmail.com ÖzetPsikodermatoloji dermatolojinin geliflmekte olan yeni bir çal›flma alan›d›r. Deri hastal›klar›n›n psikolojik ifllevlere olan etkileri ve dolay›s›yla dermatoloji ile psikosomatik t›p yak›n aras›ndaki iliflki uzun süredir bilinmesine karfl›n kan›ta dayal› bilimsel yöntem-lerin gelifltirilmesi, psikolojik etkilerin somut verilerle do¤rulanmas› ve bunlar›n tedaviye olan yans›malar› henüz gerçekleflmekte-dir. Bu makalede psikodermatolojinin bir çal›flma disiplini olarak gereklili¤i farkl› noktalardan de¤erlendirilmekte ve bu alandaki geliflmelerin gelecekteki durumu gözden geçirilmektedir. (Türkderm 2010; 44 Özel Say› 1: 55-6) Anahtar Kelimeler: Psikodermatoloji SummaryPsychodermatology is a new developing area of dermatology. It has been long recognized that dermatologic disease may affect psychological functions in dermatology patient and thus, there is a close relationship between dermatology and psychosomatic medicine. Despite this, the development of scientific methods based on the evidence-based medicine and confirmation of psychological effects via o...

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Psychosomatic Factors in Dermatology

Cited by 23 publications

References 55 publications

Psychological disorders in patients with lichen simplex chronicus: A comparative study with normal population

Psychological disorders in patients with lichen simplex chronicus: A comparative study with normal population

Therapeutic prospects of mycophenolate mofetil for the treatment of neurodermatitis

The Future of Psychodermatology

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