Psychotic symptoms, cognition and affect as predictors of psychosocial problems and functional change in first-episode psychosis

Impaired Social and Role Function in Ultra-High Risk for Psychosis and First-Episode Schizophrenia: Its Relations with Negative Symptoms

“…At first, depressive symptoms and psychosocial functioning seemed to have association with simple correlation, but it turned out to be not primarily related when we did the regression analysis. These findings were generally compatible to those of previous studies in first-episode schizophrenia1519 and UHR individuals 21222324. There were a few reports of correlations of psychosocial dysfunction with depressive symptoms in first-episode schizophrniea patients131620 and UHR individuals 252627.…”

“…In schizophrenia, there were heterogeneous findings on the relationship of psychosocial disability with psychopathologies including negative symptoms10111213141516171819 and depressive symptoms 131620. These mixed findings may be resulted from the clinical status of schizophrenia (first episode1519 vs. multi-episode or mixed),101112131416171820 psychosocial function measurement tools [objective measures101113141517181920 vs. subjective measures11121316] and other factors.…”

“…These mixed findings may be resulted from the clinical status of schizophrenia (first episode1519 vs. multi-episode or mixed),101112131416171820 psychosocial function measurement tools [objective measures101113141517181920 vs. subjective measures11121316] and other factors. In UHR, most studies found that the psychosocial impairment was associated with negative symptoms2122232425 while few reports showed the relations with depressive symptoms 252627.…”

The research evidence for schizophrenia as a neurodevelopmental disorder

“…In one of the most influential articles in the field, Michael Green () identified that neurocognition is a better predictor than symptoms, both for the course of the illness and for functional outcome. This has later been confirmed through a number of empirical studies (Allott, Liu, Proffitt & Killackey, ; Stouten, Veling, Laan, van der Helm & van der Gaag, ; Torgalsboen, Mohn & Rund, ).…”

The role of premorbid personality and social cognition in suicidal behaviour in first-episode psychosis: A one-year follow-up study

“…Some authors have proposed that ToM deficits could be a schizophrenia vulnerability marker (Sprong et al, 2007) from FEP (Bora and Pantelis, 2013). Perspective taking handicaps have been associated with negative and positive symptoms (Ventura et al, 2015), disorganisation (Vohs et al, 2014), worse psychosocial functioning (Stouten et al, 2014) and lack of insight (Konstantakopoulos et al, 2014). Previous work has also shown significant relationships between ToM deficits and suicidal behaviour in patients with schizophrenia (Duñó et al, 2009).…”