2020
DOI: 10.1007/s11136-020-02478-6
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Psychotropic polypharmacy and its association with health-related quality of life among cancer survivors in the USA: a population-level analysis

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Cited by 14 publications
(12 citation statements)
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References 29 publications
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“…The self-reported HRQoL was around 16% lower among patients on treatment with multiple pills daily compared to those with one pill once a day, consistent with previous work [ 30 32 ]. However, forgetfulness, decreased attention, and complex treatment regimens and polypharmacy are modifiable, through targeted interventions.…”
Section: Discussionsupporting
confidence: 89%
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“…The self-reported HRQoL was around 16% lower among patients on treatment with multiple pills daily compared to those with one pill once a day, consistent with previous work [ 30 32 ]. However, forgetfulness, decreased attention, and complex treatment regimens and polypharmacy are modifiable, through targeted interventions.…”
Section: Discussionsupporting
confidence: 89%
“…The results of our study indicate that forgetfulness to adhere to prescribed medications and taking more than one pill multiple times daily were negatively associated with HRQoL (− 9% and − 16% lower respectively) among a nationally representative cohort of patients who were diagnosed and received prescription medication treatment for hypertension, dyslipidemia, or both in Greece. These findings are supported by previous studies and suggest that, since these conditions can be effectively controlled and treated through medication therapy, increased compliance and less complex treatment regimens result in improved clinical outcomes, and, thus, reduce or eliminate symptoms which in turn improve functioning and HRQoL [22][23][24][25][26][27][28][29][30][31][32][46][47][48].…”
Section: Discussionsupporting
confidence: 85%
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“…As both polypharmacy status and HRQoL may change over time, especially in older adults, longitudinal studies with adequate follow-up periods are needed to assess this association. Results from previous research, which has been limited to cross-sectional studies and specific subgroups, have been inconsistent [14,[21][22][23][24][25]. Thus, the aim of this study was to investigate the association between polypharmacy status and trajectories of HRQoL in community-dwelling older adults.…”
Section: Introductionmentioning
confidence: 98%
“…(Figure 1). PRO may also help cancer patients and caregivers to better sort out major versus minor contributors to eating behavior and well-being as well as staying "ontrack" during treatment and avoiding polypharmacy or worse: ineffective, and potentially harmful supplements and unproven alternative treatments [41,74,[128][129][130][131][132]169].…”
Section: Discussionmentioning
confidence: 99%