PtAu alloy nanoflowers on 3D porous ionic liquid functionalized graphene-wrapped activated carbon fiber as a flexible microelectrode for near-cell detection of cancer

Wang, Lu; Dong, Yue; Zhang, Yan; Zhang, Zheye; Chi, Kai; Yuan, Hao; Zhao, Anshun; Ren, Jinghua; Xiao, Fei; Wang, Shuai

doi:10.1038/am.2016.189

Cited by 51 publications

(25 citation statements)

References 49 publications

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“…X‐ray photoelectron spectroscopy (XPS) is further employed to analyze the elemental chemical states of Cu 2 (NDC) 2 /PDHP and C, O, Cu elements are determined (Figure C). The C 1s spectra can be deconvoluted into three peaks at 284.6, 286.5, and 288.2 eV, which are consistent with CC/CC, CO, and CO, respectively (Figure D), consistent with the previous reports . The CC/CC, CO, and CO peaks originate from the linker of Cu 2 (NDC) 2 , corresponding to the carbon and oxygen in the benzene ring and the carboxyl group.…”

Section: Resultssupporting

confidence: 90%

“…Motivated on outstanding sensing performances and transfer mechanism of biomimetic Murray MOFs, it is highly desirable to apply Cu 2 (NDC) 2 /PDHP in the sweat lactate and glucose sensing platform. And for wearable sweat sensors, flexibility substrate plays crucial roles in real‐time monitoring during continuous movement . The mechanical stability of Cu 2 (NDC) 2 /PDHP at different bending states has been studied.…”

Section: Resultsmentioning

confidence: 99%

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Coffee Ring–Inspired Approach toward Oriented Self‐Assembly of Biomimetic Murray MOFs as Sweat Biosensor

Wang

Liu

et al. 2018

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The emergence of metal–organic frameworks (MOFs) has sparked intensive attention and opened up the possibility of “crystal engineering.” However, low conductivity, slow diffusion of guest molecules, as well as powder forms always hinder the development of MOF application, especially for biosensors and bioelectronics. Herein, a coffee ring–inspired strategy toward oriented self‐assembly of a biomimetic MOF film following Murray's law is proposed, which can effectively reduce the transfer resistance. The approach includes two types of self‐assembly, evaporation‐driven and heteroepitaxy self‐assembly, and endows the centimeter‐expanded MOF film with oriented macropores, mesopores, and micropores. The Murray MOF network enables greatly enhanced electrons and mass transfer efficiency for electrochemical sensing. Also, the newly discovered lactate and glucose sensing abilities in a wide pH hold striking potential in new generation of wearable sweat biosensors, miniature bioelectronics, and lab‐on‐a‐chip devices.

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Section: Resultssupporting

confidence: 90%

Section: Resultsmentioning

confidence: 99%

Coffee Ring–Inspired Approach toward Oriented Self‐Assembly of Biomimetic Murray MOFs as Sweat Biosensor

Wang

Liu

et al. 2018

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“…[1][2][3][4][5][6] The physical and chemical properties of bimetallic noble metal nanostructures not only depend on their chemical compositions but also are related to their morphologies. [4][5][6][7][8][9] In general, bimetallic nanostructures display remarkably improved catalytic activity and selectivity compared with the corresponding monometallic nanocrystals due to the strong ensemble and ligand effects between the different components (that is, geometrical and electronic effects). [4][5][6][7]9 Meanwhile, noble metal nanodendrites with branched arms are attracting tremendous attention for the catalytic applications due to their large surface area, unusual interconnected and porous structure and abundance of low-coordination atoms at steps and corners.…”

Section: Introductionmentioning

confidence: 99%

“…[4][5][6][7][8][9] In general, bimetallic nanostructures display remarkably improved catalytic activity and selectivity compared with the corresponding monometallic nanocrystals due to the strong ensemble and ligand effects between the different components (that is, geometrical and electronic effects). [4][5][6][7]9 Meanwhile, noble metal nanodendrites with branched arms are attracting tremendous attention for the catalytic applications due to their large surface area, unusual interconnected and porous structure and abundance of low-coordination atoms at steps and corners. 10,11 Consequently, bimetallic noble metal nanodendrites have a broad variety of applications, ranging from organic synthesis to energy conversion.…”

Section: Introductionmentioning

confidence: 99%

Bimetallic AuRh nanodendrites consisting of Au icosahedron cores and atomically ultrathin Rh nanoplate shells: synthesis and light-enhanced catalytic activity

et al. 2017

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Precise control of the morphology, composition and structure of metal nanostructures not only effectively improves their catalytic activity and durability but also enhances their range of applications. In this work, bimetallic Au@Rh core-shell nanodendrites are synthesized by a facile one-pot hydrothermal method. Physical characterizations show that the dendritic Rh consists of two-dimensional (2D) ultrathin Rh nanoplates with a thickness of approximately 1.2 nm. For the first time, Au@Rh core-shell nanostructures are used as a catalyst for the hydrogen generation reaction from aqueous hydrazine solution (N 2 H 4 = N 2 +2H 2 , HGR-N 2 H 4 ). Bimetallic Au@Rh core-shell nanodendrites exhibit improved catalytic activity and durability for the HGR-N 2 H 4 compared with commercial Rh nanocrystals, which can be attributed to the atomically ultrathin structure of 2D Rh nanoplates and the interconnected structure of nanodendrites, respectively. Under light irradiation, bimetallic Au@Rh core-shell nanodendrites show light-enhanced catalytic activity for the HGR-N 2 H 4 , originating from the distinctive localized surface plasmon resonance of Au icosahedron cores.

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“…A 3D porous nanocomposite structure was prepared on an activated carbon fiber (ACF) support by electrodepositing electrochemically reduced graphene oxide (ERGO) and AuPt alloy nanoflowers (PtAu/IL–ERGO/ACF). This system was used for the detection of H 2 O 2 released from cancer cells . The enhanced catalytic properties of the nanocomposite exhibited excellent signal amplification for the detection of H 2 O 2 near cancer cells, and the system was able to differentiate normal and breast cancer cells.…”

Section: Nanomaterial‐based Cancer Sensing Systemsmentioning

confidence: 99%

Advanced Functional Structure‐Based Sensing and Imaging Strategies for Cancer Detection: Possibilities, Opportunities, Challenges, and Prospects

Kumar

Kukkar

Hashemi

et al. 2019

Adv Funct Materials

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Cancer is the second most common cause of death in the world. The principal limitations thus far encountered in the clinical practice of probing cancer are diverse and include low sensitivity, time consumption, bulkiness, and cost. In this respect, nanomaterial (NM)-based sensing techniques are recognized as a superior alternative to efficiently resolve such limitations. A better understanding of NM-based sensing platforms is thus important so that these novel avenues can easily be explored for clinical applications. These platforms have the merits of high sensitivity, high specificity, rapid response, and easy-to-read signals. This review offers a comprehensive survey of NM-based advanced cancer-sensing techniques and will help the scientific community establish optimum sensing strategies based on an accurate assessment of the interactions between cancer biomarkers and NM-based platforms.but are not limited to, carcinoma, sarcoma, leukemia, lymphoma, non-Hodgkin lymphoma, myeloma, central nervous system cancer, lung and bronchus cancer, colon cancer, rectum cancer, prostate cancer, bladder cancer, kidney and renal pelvis cancer, endometrial cancer, pancreatic cancer, liver cancer, and thyroid cancers. [1] Moreover, the most commonly occurring cancers tend to differ by common criteria like sex and age. For example, men are at risk for prostate, lung, and colorectal cancer, women are at risk for breast, lung and colorectal cancer, and children are at risk for leukemia, brain tumors, and lymphoma. The severity of the cancer depends upon the development level or staging of the disease. [2] Likewise, the type of treatment required to treat the cancer is determined by the staging of the disease.The more severe condition of cancer is metastasis, i.e., the uncontrolled growth of cells that invade surrounding tissues. The metastasis condition of cancer can affect any organ of the body. [3] As per the WHO 2010 report on cancer, the lives of 30% patients could have been saved if the cancer was diagnosed earlier. The detection of cancer is not easy because the immune system does not necessarily consider cancerous cells as foreign bodies. However, a few changes (such as altered biomarker levels and the presence of cancerous cells in biological fluids) can be detected. [4] In general, cancer biomarkers are overexpressed proteins present in blood/serum and at the cancer cell surface. The accurate and efficient detection of these biomarkers can be useful for cancer detection. The major problem with biomarkers is their low level in the body during the earlier stages of cancer. Hence, an efficient sensor/device capable of detecting these molecules even at very low levels, if developed, could help the clinician efficiently diagnose cancer cells in the human body.The sensing techniques presently used by clinicians suffer from several limitations; specifically, they are time consuming, bulky, have low sensitivity, and are expensive. Nanomaterial (NM)-based techniques have become an important alternative to the laborious conventional...

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PtAu alloy nanoflowers on 3D porous ionic liquid functionalized graphene-wrapped activated carbon fiber as a flexible microelectrode for near-cell detection of cancer

Cited by 51 publications

References 49 publications

Coffee Ring–Inspired Approach toward Oriented Self‐Assembly of Biomimetic Murray MOFs as Sweat Biosensor

Coffee Ring–Inspired Approach toward Oriented Self‐Assembly of Biomimetic Murray MOFs as Sweat Biosensor

Bimetallic AuRh nanodendrites consisting of Au icosahedron cores and atomically ultrathin Rh nanoplate shells: synthesis and light-enhanced catalytic activity

Advanced Functional Structure‐Based Sensing and Imaging Strategies for Cancer Detection: Possibilities, Opportunities, Challenges, and Prospects

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