2019
DOI: 10.1186/s12886-018-1020-y
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Pterygium surgery combined with the removal of a missed occult iris foreign body detected incidentally during pterygium examination: a case report

Abstract: BackgroundAn occult foreign body may be retained in patient with small self-sealing wound and no decreased visual acuity without complete examination. Here we report a case of a retained occult ferrous iris foreign body detected incidentally during pterygium examination.Case presentationA 69-year-old man presented to our ophthalmology department because of foreign body sensation and persistent redness in both eyes for 2 years. In the left eye, a pterygium, paracentral corneal opacity and a vertically oval pupi… Show more

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Cited by 4 publications
(5 citation statements)
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“…The authors noticed a reduction in the number of HF on the OCT scans following the administration of conbercept, asserting that HF on OCT scans are reliable biomarkers of individual response to conbercept treatment in patients with DME. A greater number of HF on the OCT scans at baseline demonstrates a more active DME and predicts worse final best-corrected visual acuity following conbercept treatment [ 3 ].…”
Section: Developmentmentioning
confidence: 99%
See 1 more Smart Citation
“…The authors noticed a reduction in the number of HF on the OCT scans following the administration of conbercept, asserting that HF on OCT scans are reliable biomarkers of individual response to conbercept treatment in patients with DME. A greater number of HF on the OCT scans at baseline demonstrates a more active DME and predicts worse final best-corrected visual acuity following conbercept treatment [ 3 ].…”
Section: Developmentmentioning
confidence: 99%
“…Diabetic retinopathy (DR) is the leading cause of blindness in people under 75 years of age in developed countries [ 1 , 2 ]. Diabetic macular edema (DME) can occur at any stage of DR, being the major cause of central vision loss in patients with diabetes mellitus (DM) [ 3 ]. The World Health Organization estimated that by the year 2030, there will be approximately 366 million individuals suffering from DM [ 4 ].…”
Section: Introductionmentioning
confidence: 99%
“…Any patient presenting with penetrating ocular injury should be suspected of having IOFB and should be followed up closely. Indications of a possible IOFB include small self-sealing wounds, iris transillumination defects, iris heterochromia, irregular pupils, and focal lens opacities [24]. ere is no consensus on whether ILFBs should be removed.…”
Section: Discussionmentioning
confidence: 99%
“…There is no standard treatment protocol currently but the various therapeutic options described for AIRs, in the previous literature[ 7 10 21 22 23 39 40 51 59 60 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 ] are (1) immunosuppression through systemic and/or topical (intravitreal/sub-tenon/depot) corticosteroids, (2) immunomodulators like cyclosporine (calcineurin inhibitor which prevents IL-2 transcription), infliximab (anti-TNFα antibody), mycophenolate mofetil (IMP dehydrogenase inhibitor, preventing purine synthesis), azathioprine (purine antimetabolite), (3) biologics such as monoclonal antibodies like rituximab (anti-CD20 antibody), alemtuzumab (anti-CD52 antibody), ipilimumab (antagonist antibody against cytotoxic T-lymphocyte antigen-4), tocilizumab (anti-IL-6 receptor antibody), sarilumab (anti-IL-6 receptor antibody), (4) and others like intravenous immunoglobulin (IVIG), plasmapheresis. IVIG has been hypothesized to have several mechanisms of action like neutralization of autoantibodies, binding of complement components, inhibition of dendritic cells maturation, modulation of intercellular adhesion, and contribution of IgG4.…”
Section: Treatmentmentioning
confidence: 99%