2012
DOI: 10.1136/gutjnl-2012-302514c.8
|View full text |Cite
|
Sign up to set email alerts
|

PTU-008 A reproducible, clinically-relevant, intensively-managed, pig model of acute liver failure for testing of therapies aimed to prolong survival

Abstract: Introduction Hospitalisations from acetaminophen poisoning are increasing (1999, n¼39 045; 2010, n¼52 707. UK, NHS admissions). For the most serious cases there are no effective therapies to assist recovery or prolong survival apart from liver transplantation, which remains a limited resource. We report a clinically-relevant, intensively-managed, model of ALF, which mimics the human condition and has a predictable survival time, for testing of new potential therapies. Methods Nine, 30e40 kg, female pigs were a… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

0
0
0

Publication Types

Select...

Relationship

0
0

Authors

Journals

citations
Cited by 0 publications
references
References 2 publications
0
0
0
Order By: Relevance

No citations

Set email alert for when this publication receives citations?