Pubertal fenvalerate exposure impairs cognitive and behavioral development partially through down-regulating hippocampal thyroid hormone receptor signaling

Yang, Yang; Zhan, Feng; Wang, Ye-cheng; Wang, Bo; Shi, Meng-Xing; Guo, Ce; D, Xu; Meng, Xiu-Hong

doi:10.1016/j.toxlet.2020.07.020

Cited by 9 publications

(2 citation statements)

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“…Increased anxiety activities were observed only in females exposed to fenvalerate. There is evidence that exposure to low-dose fenvalerate impairs behavioral and cognitive development in a gender-dependent manner [64]. As well in the same year, (Fatemeh Yousefnezhad Malekia et al) determined the quantities of Fenvalerate residue in grapes by the vortex-assisted surfactant-enhanced emulsification liquid-liquid microextraction (VSLLME) method.…”

Section: 42fenvaleratementioning

confidence: 99%

A brief review of recent advances in surface-enhanced Raman spectroscopy and microfluidics technology for the ultrasensitive detection of pesticides.

DOUASS

SAMOUDI²,

BENDAOU

et al. 2022

Egypt. J. Chem.

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The pesticide is any substance used to prohibit, destroy, or control pests, such as insects, fungus, rodents or, undesirable plant species that cause damage during crop production and storage. There are a lot of traditional methods to detect pesticides, among them gas chromatography (GC), high-performance liquid chromatography (HPLC), and their combinations with ultraviolet (UV) or mass spectroscopy. Nevertheless, these conventional techniques have several limitations, involving complicated pre-treatment steps, requiring expensive instruments, operational difficulty, lack of instrument portability, and difficulties in real-time monitoring. Surface-enhanced Raman spectroscopy (SERS) is one of the current leading techniques widely applied for the ultrasensitive detection of pesticides molecules. SERS take advantage to combine the high specificity of Raman scattering with the signal amplification of electromagnetic enhancement provided by the excitation of surface Plasmon resonances in metallic nanostructures, together with the charge transfer mechanisms established between metal surfaces and analytes. In this brief review, types of classification of pesticides that can be classed has been reported. These classifications can provide valuable information on the chemistry of pesticides. The state of art of SERS, including a theoretical background study, is briefly described. Finally, some recent development and applications of optical and analytical techniques for pesticides detection has been summarised, a particular study will be focused on SERS combined with microfluidic technology.

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Section: 42fenvaleratementioning

confidence: 99%

A brief review of recent advances in surface-enhanced Raman spectroscopy and microfluidics technology for the ultrasensitive detection of pesticides.

DOUASS

SAMOUDI²,

BENDAOU

et al. 2022

Egypt. J. Chem.

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“…It was suggested that slight deviations in normal brain T3 levels might lead to the cognitive deterioration [44]. Additionally, either reduced serum-free T3 or downregulating hippocampal thyroid hormone receptor signaling could develop cognitive and behavioral impairment in mice [45,46]. Since the association between hyperthyroidism and/ or hypothyroidism with dementia has already been studied and is still being investigated, it is necessary to consider the underlying pathology and mechanisms of this association and thus modify the management of dementia.…”

Section: Thyroid Disorders and Cognitive Impairmentsmentioning

confidence: 99%

Thyroid Disorders and Development of Cognitive Impairment: A Review Study

Khaleghzadeh‐Ahangar¹,

Talebi²,

Mohseni‐Moghaddam³

2021

Neuroendocrinology

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Dementia is a neurological disorder that is spreading with increasing human lifespan. In this neurological disorder, memory and cognition are declined and eventually impaired. Various factors can be considered as the background of this disorder, one of which is endocrine disorders. Thyroid hormones are involved in various physiological processes in the body; one of the most important of them is neuromodulation. Thyroid disorders, including hyperthyroidism or hypothyroidism, can affect the nervous system and play a role in the development of dementia. Despite decades of investigation, the nature of the association between thyroid disorders and cognition remains a mystery. Given the enhancing global burden of dementia, the principal purpose of this study was to elucidate the association between thyroid disturbances as a potentially modifiable risk factor of cognitive dysfunction. In this review study, we have tried to collect almost all of the reported mechanisms demonstrating the role of hypothyroidism and hyperthyroidism in the pathogenesis of dementia.

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