Pubertal timing and a family history of hypertension: Prospective cohort study

Zheng, Wei; Suzuki, Kohta; Sato, Mitsuaki; Yokomichi, Hiroshi; Shinohara, Ryoji; Yamagata, Zentaro

doi:10.1111/ped.12821

Cited by 3 publications

(1 citation statement)

References 24 publications

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“…A better understanding of how pubertal timing affects the relation between ADHD symptoms in early childhood and later externalizing and internalizing symptoms will enable us to develop a more comprehensive understanding of ADHD symptomatology, comorbidities, prevention, and treatment plan development for youth with elevated ADHD symptoms. We used estimated age at peak height velocity (APHV), a surrogate and objective measure for pubertal timing (specifically, the age at which linear growth during puberty is fastest), to explore the relation between sex differences and pubertal timing, as sex differences in APHV are well established in the literature (Kelly et al, 2014;O'Neill et al, 2022;Zheng et al, 2013). We anticipate finding differences by sex in the impact of pubertal timing and how it may moderate the relation between ADHD symptoms and the later expression of internalizing and externalizing symptoms.…”

Section: Current Studymentioning

confidence: 99%

Prediction of internalizing and externalizing symptoms in late childhood from attention-deficit/hyperactivity disorder symptoms in early childhood

Mlodnicka,

Mansolf,

Chandran

et al. 2024

Dev Psychopathol

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Limited analyses based on national samples have assessed whether early attention-deficit/hyperactivity disorder (ADHD) symptoms predict later internalizing and externalizing symptoms in youth and the influence of sex and pubertal timing on subsequent psychiatric symptoms. This study analyzed data (n = 2818) from the Environmental influences on Child Health Outcomes Program national cohort. Analyses used data from early childhood (mean age = 5.3 years) utilizing parent-reported ADHD symptoms to predict rates of internalizing and externalizing symptoms from late childhood/adolescence (mean age = 11.9 years). Within a subsample age at peak height velocity (APHV) acted as a proxy to assess pubertal timing from early childhood (mean age = 5.4 years) to adolescence (mean age = 12.3 years). Early-childhood ADHD symptoms predicted later psychiatric symptoms, including anxiety, depression, aggressive behavior, conduct problems, oppositional defiant disorder, and rule-breaking behavior. Earlier APHV was associated with increased Conduct Disorder symptoms from late childhood to adolescence for females only. A stronger relation between ADHD symptoms and later aggression was observed in females with earlier APHV, whereas this same pattern with aggression, conduct problems and depression was observed in males with later APHV. Clinicians should consider that both young girls and boys with elevated ADHD symptoms, particularly with off-set pubertal timing, may be at risk for later psychiatric symptoms.

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Section: Current Studymentioning

confidence: 99%

Prediction of internalizing and externalizing symptoms in late childhood from attention-deficit/hyperactivity disorder symptoms in early childhood

Mlodnicka,

Mansolf,

Chandran

et al. 2024

Dev Psychopathol

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Family History of Hypertension and Cobalt Exposure Synergistically Promote the Prevalence of Hypertension

Zhang

Zeng

Qin

et al. 2021

Biol Trace Elem Res

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Change of weight status during school age and its association with late adolescent blood pressure: Results from a 15-year longitudinal study in China

Wang

Dong

Huang³

et al. 2022

Front. Public Health

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BackgroundChange in obesity risk could be related to shift in high blood pressure (HBP) risk, while individualized influence of weight change on high blood pressure is in need of exploration.MethodsA total of 16,446 children (53.47% boys) and 13,9021 effective annual measurements from 2006 to 2020 were recruited. Children's weight status, both at baseline and endpoint, was categorized as underweight, normal, overweight, and obese according to the age and sex-specific Body Mass Index z scores. HBP at late adolescence was defined with the last two measurements for each child. Populational attributable risk (PAR) of weight trait on HBP risk was calculated.ResultsCompared to children who maintained normal weight during follow-up, staying obese was associated with the highest HBP risk with OR of 6.39 (95% CI: 4.46, 9.15; p < 0.001) and PAR of 28.71% (95% CI: 21.58, 35.54) in boys, and OR of 6.12 (95% CI: 2.80, 13.37; p < 0.001) and PAR of 12.75% (95% CI: 4.29, 21.02) in girls. Returning from obese to normal weight was associated with lowered HBP risk, with ORs of 1.07 (95% CI: 0.69, 1.66; p = 0.771) in boys and 0.73 (95% CI: 0.25, 2.12; p = 0.566) in girls.ConclusionWeight loss program could be effective to reduce HBP risk during school age, while the underlying mechanism needs further exploration.

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Pubertal timing and a family history of hypertension: Prospective cohort study

Cited by 3 publications

References 24 publications

Prediction of internalizing and externalizing symptoms in late childhood from attention-deficit/hyperactivity disorder symptoms in early childhood

Prediction of internalizing and externalizing symptoms in late childhood from attention-deficit/hyperactivity disorder symptoms in early childhood

Family History of Hypertension and Cobalt Exposure Synergistically Promote the Prevalence of Hypertension

Change of weight status during school age and its association with late adolescent blood pressure: Results from a 15-year longitudinal study in China

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