“…Currently, the Centers for Disease Control and Prevention and others recommend that all substance abusers receive the HAV and HBV vaccine if they have not already been exposed or immunized (Centers for Disease Control and Prevention, 1999; Craig, Schaffner, 2004; Crowcroft, Walsh, Davison, & Gungabissoon, 2001; Hershey, Schowalter, & Bailey, 2005; Poland, & Jacobson, 2004; Poland, 2005; Quaglio, Lugoboni, Mezzelani, Des Jarlais, & Lechi, 2006). A substantial proportion of substance abusers have underlying chronic liver disease due to HCV infection and are at increased risk of acute liver failure and death if they were to become superinfected with HAV or HBV (Akriviadis, & Redeker, 1989; Vento, Garofano, Renzini, Cainelli, Casali, Ghironzi, Ferraro, & Concia, 1998; Koff, 2001; Cooksley, 2004; Reiss, & Keeffe, 2004; Keeffe, 2005).…”