“…It did inform proactive public intervention and sanitary legislation that aimed at protecting the populations' health and regulating the complex metabolism between cities and their surroundings. Whether it is in the Islamicate or the later Ottoman Empire, Medieval English towns or cities in France the Lowlands, the Italian peninsula or Adriatic towns in what is today Croatia (Leguay, 1999(Leguay, , 2002Vanzan Marchini, 2000;Geltner, 2012;Rawcliffe, 2013;Grmek, 1980;Petaros et al, 2013;Blažina-Tomić and Blažina, 2015;Skelton, 2015 for a later period), historians have brought to light a longer tradition of preventive measures that since the early thirteenth To be published in Studies in History and Philosophy of Science (2021), Special Issue, "What counts as environment in biology and medicine: Historical, philosophical and sociological perspectives", Edited by Jan Baedke, Tatjana Buklijas. Pls refer and cite from final version century operated "for the benefit and health of all" showing a significant level of concern for the natural and the built environment (Geltner, 2019a for a rich overview).…”