This chapter presents a selection of interdisciplinary approaches used within the study of Roman visual culture. Iconology, creolization, hybridization, and entanglement are discussed alongside the problems of ‘Romanization’. Emphasis is given to the idea that images, like objects, have a biography and live a social life. Images in this sense can have a range of meanings depending on context and user. The role of images in Roman imperialism and memory is explored, with case studies including funerary contexts, the conquest of Egypt in 30 bce, the formation of Nemausus as a colony, and the siege of Jerusalem in 70 ce.