Utilizing the QCD sum rule approach to the behavior of the ω meson in nuclear matter we derive evidence for in-medium changes of particular four-quark condensates from the recent CB-TAPS experiment for the reaction γ + A → A ′ + ω(→ π 0 γ) with A = Nb and LH2. The chiral condensate qq is an order parameter for the spontaneous breaking of chiral symmetry in the theory of strong interaction (cf. e.g. [1] for introducing this topic). The role of qq is highlighted, e.g., by the GellMann-Oakes-Renner relation m 2 π f 2 π ∝ − qq (cf. [2]; the explicit chiral symmetry breaking is essential for a finite pion mass m π , while the relation of the pion decay constant f π to qq qualifies the latter as an order parameter) or by Ioffe's formula M N ∝ − qq for the nucleon mass (cf. [3] and in particular the discussion in [4]). There is growing evidence that the quark-gluon condensate is another order parameter [5]. The QCD trace anomaly related to scale invariance breaking gives rise to the gluon condensate. There are many other condensates characterizing the complicated structure of the QCD vacuum. In a medium, described by temperature and baryon density n, these condensates change, i.e., the ground state is rearranged. Since hadrons are considered as excitations above the vacuum, a vacuum change should manifest itself as a change of the hadronic excitation spectrum. This idea triggered widespread activities to search for in-medium modifications of hadrons. Such in-medium modifications of hadronic observables are found (cf. the lists in [6,7]), and it is timely to relate them to corresponding order parameters.We deduce here evidence for a noticeable drop of inmedium four-quark condensates in cold nuclear matter from results of the recent CB-TAPS experiment [6] for the reaction γ + A → A ′ + ω(→ π 0 γ). The CB-TAPS collaboration observed the occurrence of additional lowenergy ω decay strength for a Nb (A = 93) target compared to a LH 2 (A = 1) target. The link of observables to quark and gluon condensates is established by QCD sum rules [8], which are expected to be sensitive to four-quark condensates in the vector channels [9]. Four-quark condensate combinations which contain only left-right helicity flipping terms (as the chiral condensate does) represent other order parameters of chiral symmetry.Concentrating on the iso-scalar part of the causal current-current correlator [3]here for the ω meson with the current j ω µ = ūγ µ u +dγ µ d /2 and nuclear matter states |Ω (the symbol T means time ordering, and u, d denote quark field operators), an operator product expansion and a Borel transformation (cf. [3,10] for arguments in favor of Borel sum rules) of the twice-subtracted dispersion relation result inwhere Π ω (0, n) = 9n/(4M N ) with the nucleon mass M N is a subtraction constant having the meaning of Landau damping or ω N forward scattering amplitude, and the coefficients c j contain condensates and Wilson coefficients; M is the Borel mass. The first coefficients c j have been spelled out in many papers (cf.[11] for our ...