PUK7 Cost of Illness of Overactive Bladder Syndrome in Hungary

Abstract

HD (6,547€-95%CI: 5,727€-7,366€-) was significantly higher (pϽ0.001) than TX (5,079€-95%CI:4,127€-6,030€-) or APD (4,359€-95%CI:3,064€-5,655€-) but not CAPD (5,785€-95%CI:4,302€-7,269€-). PPYLtc was higher in HD than in TX, APD or CAPD in all the provided scenarios. CONCLUSIONS: APD is the alternative with the lowest impact on indirect costs due to morbidity. Besides, TX recipients also have higher rates of employment than HD and require less disability benefits. OBJECTIVES:Little information is available on the prevalence of post-transplant events and resource utilization associated with such events in renal transplant (RT) patients in clinical practice in Germany. The PORTRAIT study aims to describe the health care resources used and to estimate the cost of managing post-transplant patients using observational data from transplant databases and physician questionnaires from transplant centers across Europe. Aggregated study results have been previously communicated; this abstract describes the results from two German centers. METHODS: A retrospective observational study was undertaken in which resource usage over three years was employed to derive costs from a third party perspective, with results stratified by glomerular filtration rate (GFR) status at one-year post transplant. Descriptive statistics were used to detail medical resource use and its costs. Post-transplant events considered were: hospitals stays, delayed graft function, outpatient appointments, laboratory tests, anaemia, hypertension, dyslipidaemia and infections. Immunosuppressant drug costs were not considered in this analysis. RESULTS: Four hundred and fourteen patients from both sites were included in the analysis. The total three-year cost of post-transplant care by GFR at one year varies from a minimum of €20,632 per patient to a maximum of €43,163 per patient. The average three-year costs decrease as a result of improved graft functioning status (increased GFR) at one year. The average three-year costs for a patient with a GFRՆ45mL/ min/1.73 m2 at one year are 40% lower than those patients with a GFRϽ30 mL/ min/1.73 m2. CONCLUSIONS: In line with the multinational results, the German results provide evidence that posttransplant resource usage in a real-life treatment setting increases as post-transplant renal function worsens. Therefore management strategies that promote renal function post transplant are likely to provide important resource savings to the health care system.

The impact of age, gender and severity of overactive bladder wet on quality of life, productivity, treatment patterns and satisfaction

“…4,[7][8][9][10] However, there is limited information on how HRQoL varies with UUI severity, gender or age among those with OAB wet. OAB in general and OAB wet also impose a burden on patient productivity, and employment and medical resource use, [7][8][9][11][12][13][14][15] and UUI severity is significantly associated with productivity loss. 7 The objectives of this study were to determine the impact of idiopathic OAB wet severity, age and gender on HRQoL, productivity, treatment patterns and treatment satisfaction.…”