Pulmonary Acute Lesions After Caustic Exposure

Advenier, Anne‐Sophie; Grandmaison, Geoffroy Lorin de la

doi:10.29245/2689-999x/2017/2.1119

Cited by 3 publications

(1 citation statement)

References 21 publications

(23 reference statements)

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“…austic ingestion continues to be a significant problem worldwide especially in developing countries and particularly in children. Indeed, potentially catastrophic presentations and lifelong complications resulting from corrosive ingestion are one of the most challenging situations in pediatric medical practice (Advenier & Grandmaison, 2018;Di-Nardo et al, 2020).…”

Section: Introductionmentioning

confidence: 99%

The Potential Role of Procalcitonin Compared to C-reactive protein and Neutrophil Lymphocyte Ratio in Prediction of Severity and Outcomes of Acute Corrosive Ingestion

Saleh,

Abdel Salam,

Abou Anza

et al. 2024

Ain Shams Journal of Forensic Medicine and Clinical Toxicology

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Background: Caustic ingestion in children is considered a serious healthcare issue worldwide due to its high morbidity and mortality rates. Aim: The present study aimed to evaluate the potential role of procalcitonin (PCT) compared to C-reactive protein (CRP) and neutrophil lymphocyte ratio (NLR) in assessment of severity and prediction of outcomes of acute corrosive ingestion for early intervention and better prognosis. Methods: This prospective study was conducted on 60 patients aged from 6 months to 12 years, who were admitted to poison control center, Ain Shams University Hospitals with diagnosis of acute caustic ingestion. Demographic, clinical data and blood samples were collected from each patient, with biomarkers' assessment within 24 hours post caustic ingestion. Results: The majority of patients were males (70%) with median age 1.5 years. Acute and/or chronic complications occurred in 43.3% of the studied patients. Significantly higher levels of PCT, CRP and NLR were detected in complicated patients, as well patients with DROOL score ≤4. Procalcitonin level <1.4 ng/mL was the most specific biomarker (94.12%) with the highest positive predictive value (90.5%) in predicting complications occurrence, whereas CRP level <9.6 mg/L was the most sensitive biomarker (100%). Conclusion: This study supports the role of PCT, CRP and NLR as reliable biomarkers in early predicting the severity and outcomes of corrosive ingestion in children. PCT seemed to be superior to CRP and NLR in predicting complications post caustic ingestion.

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Section: Introductionmentioning

confidence: 99%

The Potential Role of Procalcitonin Compared to C-reactive protein and Neutrophil Lymphocyte Ratio in Prediction of Severity and Outcomes of Acute Corrosive Ingestion

Saleh,

Abdel Salam,

Abou Anza

et al. 2024

Ain Shams Journal of Forensic Medicine and Clinical Toxicology

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Health risk assessment of inhalation exposure to dry fogging of hydrogen peroxide in a dental clinic during the COVID-19 pandemic

Hesam

Shekarloo

Atamaleki

et al. 2022

Environ Sci Pollut Res

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After the outbreak of COVID-19, many dental clinics use dry fogging of hydrogen peroxide (H 2 O 2 ) to disinfect the air and surfaces. Inhalation of highly concentrated solutions of H 2 O 2 may cause severe respiratory problems. This study aimed to estimate the health risk assessments of inhalation exposure to dry fogging of H 2 O 2 in a dental clinic. This cross-sectional, descriptive-analytical study was performed to determine the inhalation exposure and health risk of 9 dental clinic staff with H 2 O 2 in six rooms. Occupational exposure to H 2 O 2 was assessed using the OSHA VI-6 method and a personal pump with the flow rate of 500 mL/min connected to the midget fritted-glass impinger containing 15 mL of TiOSO 4 collecting solution. The health effects of H 2 O 2 exposure were assessed using a respiratory symptoms questionnaire. The health risk assessment of inhaled exposure to H 2 O 2 was also performed using the method provided by the Singapore occupational health department. The mean respiratory exposure of clinic staff to H 2 O 2 was ranged from 1.3 to 2.83 ppm for six rooms which was above the limits recommended by international organizations. Dyspnea (44.4%), cough (33.3%), and nasal burning (22.2%) were the most prevalent health problems. The results also showed a medium risk for endodontics and surgery, and lower risk for periodontics, restorative care, orthodontics, and prosthetics. The results of this study indicate that when using an automated hydrogen peroxide–vapor fogger, calculating the spraying time based on room volume and using the rooms after 30 min of fogging is very important and can greatly reduce the risk ranking.

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The Diagnosis of a Case of Household Cleaner Fatality

Das

Rahman

Hanuman

et al. 2020

Am J Forensic Med Pathol

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Household cleaners are an unavoidable entity in our routine domestic life. They are available either in company-labeled bottles or locally made unlabeled bottles especially in the developing countries. In this report, we are discussing a case of fatal ingestion of household cleaner, which was stored in an unlabeled bottle. The deceased developed features of gastrointestinal irritation, such as vomiting and pain in throat and abdomen. He also had features of aspiration such as cough and chest crepitation. Finally, he developed metabolic acidosis, gastric perforation, respiratory failure, and died within a day. The autopsy features such as teeth discoloration, corrosion of mouth and lips, and histopathological findings helped us in concluding that the ingredients contained some corrosive mineral acid. This case highlights the importance of histopathological examination of viscera in alleged cases of household cleaner poisoning where toxicological analysis of viscera gives negative results.

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Pulmonary Acute Lesions After Caustic Exposure

Cited by 3 publications

References 21 publications

The Potential Role of Procalcitonin Compared to C-reactive protein and Neutrophil Lymphocyte Ratio in Prediction of Severity and Outcomes of Acute Corrosive Ingestion

The Potential Role of Procalcitonin Compared to C-reactive protein and Neutrophil Lymphocyte Ratio in Prediction of Severity and Outcomes of Acute Corrosive Ingestion

Health risk assessment of inhalation exposure to dry fogging of hydrogen peroxide in a dental clinic during the COVID-19 pandemic

The Diagnosis of a Case of Household Cleaner Fatality

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