Pulmonary and intracerebral plasmacytomas in a patient without multiple myeloma: A case report

Abstract

Extramedullary plasmacytoma of the lung or brain parenchyma is rare. We report herein a case of extramedullary plasmacytoma involving both the lung and parenchymal brain. We review the literature, comparing and contrasting the current case. Am. J. Hematol. 73:131-134, 2003.

Dural plasmacytoma mimicking meningioma in a young patient with multiple myeloma

“…Radiological findings of intracranial MM or plasmacytoma are not specific. They may mimic lymphoma, metastasis, sarcoma of the dura mater, osteochondroma, infectious meningitis or meningioma [27,28]. The authors also examined the mass histopathologically.…”

Extramedullary Plasmacytoma of the Lung – Rather a Disseminated than a Localized Disease? – A Case Report of a Primary Pulmonary Plasmacytoma Showing Distinct Signs of Systemic Spread

“…Additionally, the affection of multiple sites as seen in our case -although not biopsy proven -can be verified by PET-CT imaging. General recommendations for treatment of PPP include chemotherapy in cases of multifocal occurrence, radiation therapy, and/or surgical resection [12,13,14]. In cases of disease dissemination, systemic therapy approaches such as high dose chemotherapy and autologous stem cell transplantation are indicated.…”

Aggressive and fatal extramedullary plasmacytoma: a report of two cases

“…Disseminated EMP with or without bone marrow involvement has been reported only rarely. Seven cases reported in refs (1–7) as well as patients 1 and 2 showed aggressive and fatal EMP. They were between 51 and 80 years (mean: 66 years), and consisted of six men and three women; four cases showed monoclonal protein in serum, two BJP, and all of them died after 2 and 54 months (mean: 15 months).…”

“…The third had unusual EMPs occurring sequentially in the testis, subcutaneous tissues, and heart (3). The last had pulmonary and intracerebral plasmacytomas and the mass was extending through the chest into the subcutaneous tissue (4). Tumor invasions were demonstrated microscopically in the subcutaneous tissues, nasal cavity, and stomach in patient 1, and in the right orbit and liver in patient 2; furthermore, upon clinical examination, they were detected in the lymph nodes and abdomen in the former, and in lymph nodes in the latter.…”