Pulmonary and testicular tuberculosis in one patient caused by Mycobacterium tuberculosis with different genotypes

Lan, Yuanbo; Chen, Ling; Zhang, Hong

doi:10.3855/jidc.11063

Cited by 6 publications

(4 citation statements)

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“…K. Chamberlin et al [69] приводят случай генерализованного туберкулеза у 25-летнего иммунокомпетентного пациента -мигранта в США из Индии, неблагополучной в отношении туберкулеза страны. В течение 3 мес.…”

Section: наблюдения из практикиunclassified

“…Микобактерия туберкулеза ни из одного источника ни одним методом обнаружена не была, однако полифокальная биопсия позволила подтвердить диагноз патоморфологически. После успешного курса стандартной полихимиотерапии пациент был выписан из клиники [69].…”

Section: наблюдения из практикиunclassified

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Tuberculosis of the testis and its appendages

Kulchavenya

2022

Medicinskij sovet

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Tuberculosis of the genitourinary system has not lost its relevance. During the years of the pandemic of a new coronavirus infection, the number of newly diagnosed cases of tuberculosis of all localizations has decreased, but their structure has become more severe and mortality has increased. There is a wide variation in the statistics of urogenital tuberculosis (UGT) in the literature. The true incidence of scrotal tuberculosis is not known; at the end of the last century, it was believed that it was 7% of all cases of tuberculosis. It is believed that the share of isolated tuberculosis of the genital organs of men accounts for no more than 30% of all localizations of UGT, and most often tuberculosis develops in the epididymis. The spread of M. tuberculosis to the organs of the scrotum, as a rule, occurs by the hematogenous route from the primary focus in the lungs or kidney. However, the infection can also spread retrogradely from the prostate and seminal vesicles to the epididymis and testicles. Tuberculosis of the testis and its epididymis is often complicated by infertility and the formation of fistulas. This disease has no pathognomonic symptoms. Differential diagnosis is carried out between tuberculous epididymo-orchitis, testicular tumor, testicular torsion, bacterial epididymo-orchitis. Ultrasound examination is of great diagnostic value in tuberculosis of the scrotal organs. The ultrasound picture in tuberculosis of the testis and its epididymis is divided into 4 types: diffuse enlargement, heterogeneous hypoechogenicity; diffuse increase, uniform hypoechogenicity; nodular enlargement, heterogeneous hypoechogenicity; miliary dissemination. The world literature does not describe an example of tuberculosis of the scrotal organs, when the disease would be diagnosed during the patient’s initial visit to the doctor. As a result of late diagnosis or low suspicion for TB, up to 70% of patients undergo unnecessary surgery, although TB orchiepididymitis can be treated medically. The lecture also analyzed a number of clinical observations.

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Section: наблюдения из практикиunclassified

Tuberculosis of the testis and its appendages

Kulchavenya

2022

Medicinskij sovet

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“…Частота бактериологических находок значительно различается в зависимости от используемых методов. Применение всего арсенала современных методик, в первую очередь молекулярно-генетических, позволяют существенно повысить вероятность обнаружения M. tuberculosis в патологическом материале [48][49][50][51][52].…”

Section: результатыunclassified

Mistakes in the diagnosis of tuberculous orchiepididymitis.

Kulchavenya¹,

Baranchukova²

2022

ECU

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Introduction. Everywhere there is a weighting of the structure of urogenital tuberculosis. Tuberculosis of the testis and its epididymis is difficult to diagnose because it does not have pathognomonic symptoms; the diagnosis cannot be verified microbiologically in the study of ejaculate or prostate secretion, however, it is possible to detect a pathogen in biopsy specimens or surgical material. Materials and methods. Search results were analyzed in the scientific databases eLibrary, PubMed, Web of Science, Embase, Cochrane Library and PEDro, Wang-fang and Cnki, Edline for the queries «urogenital tuberculosis», «tuberculosis of the male genital organs», «tuberculosis testicles», «tuberculosis of the epididymis», «tuberculous epididymitis», «tuberculous orchiepididymitis», «diagnosis». Results. An isolated lesion of the scrotum is observed with testicular neoplasms, bacterial epididymo-orchitis, genitourinary sarcoidosis, inguinal-scrotal hernia, and hydrocele. Since oncological diseases cause the greatest concern, misinterpretation of clinical and laboratory data and neglect of the epidemic history can lead to an erroneous diagnosis and unnecessary orchiectomy. At best, the patient is initially diagnosed with bacterial epididymo-orchitis and given antibiotic therapy. At the same time, the wrong choice of antibiotic can subsequently make it impossible to identify the pathogen and distort the pathomorphological picture. Description of the clinical case. The article presents a case of incorrect tactics in the treatment of a patient with tuberculous epididymitis, erroneously diagnosed as an «epididymal cyst». Neglect of microbiological data led to the formation of a fistulous form of orchiepididymitis. Conclusions. The diagnosis of tuberculous orchiepididymitis is difficult. With the help of radiation diagnostic methods, tuberculosis of the testicle and apidymis can be suspected; to confirm the diagnosis, identification of the pathogen or the presence of specific pathological signs is required. High vigilance is required for tuberculosis when examining a patient with complaints of enlargement and tenderness of the scrotum.

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“…Control of Mycobacterium tuberculosis can infect several organs of the body, the lungs which are often infected. There are two types of Mycobacterium tuberculosis bacteria found in the patient's body, namely bacteria through inhalation contained in droplets into the patient's respiratory tract (per inhalation) and transmission through direct contact (per continuity) [4]. Spots are an infection that appears white spots due to Mycobacterium tuberculosis bacteria entering the patient's lungs and damaging lung tissue through the air and then multiplying into colonies.…”

Section: Introductionmentioning

confidence: 99%

Model of Chlor Gas Electrolyzer from Salt Water Electrolysis as A Disinfectant for Room Air Microorganisms for TB Patients

Ganefati

Narto

Yamtana

et al. 2022

IOP Conf. Ser.: Earth Environ. Sci.

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Based on the laboratory test in book two, the results obtained: there is an effect of disinfecting the room air using Chlor gas from the electrolysis of saltwater on the decrease in the number of germs in the room air. The results of laboratory tests for room air disinfection using Chlor gas from the electrolysis of salt water or NaCl on exposure within 10 minutes, the content of Chlor gas is 0.0216 ppm and meets the quality standard. The number of airborne germs measured does not exceed 700 colonies/m3 of air. Until now, the electrolysis model with its variations has not been found to reduce airborne bacteria in TB patients with TB. The purpose of this study was to determine the effect of various electrolysis models on the reduction of indoor air bacteria in TB patients. This study uses an experimental type with pre-test and post-test designs. The independent variables in this study were various models of electrolysis and the dependent variable was the decrease in airborne bacteria in the TB patient room. All TB patients in the working area of Puskesmas throughout Yogyakarta as many as 83 Puskesmas became a population in this study. Meanwhile, all TB patients in the working area of Gamping II Public Health Center, Sleman, were the samples in this study. This study shows that there is an effect of room disinfection with the Electrolysis method on the reduction of room bacteria (P = 0.000), and the Electrolysis model one is the tool that reduces bacteria the most, which is 51.0 x 10-5 CFU/m3 (60.5%). The results of the study are recommended to be tested for acceptance of the Electrolysis I, II, and III models by the public.

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Pulmonary and testicular tuberculosis in one patient caused by Mycobacterium tuberculosis with different genotypes

Cited by 6 publications

References 13 publications

Tuberculosis of the testis and its appendages

Tuberculosis of the testis and its appendages

Mistakes in the diagnosis of tuberculous orchiepididymitis.

Model of Chlor Gas Electrolyzer from Salt Water Electrolysis as A Disinfectant for Room Air Microorganisms for TB Patients

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