Pulmonary Artery Pressure Profile in Atrial Septal Defect (ASD) Patients

Abstract

The objective of this study was to see the incidence of pulmonary hypertension and its age distribution in atrial septal defect (ASD) patients in our population. A total of 58 ASD (secundum type) patients were included in the study. The diagnosis was done with echocardiography. Subsequently patients under went cardiac catheterization and their pulmonary artery (PA) mean pressure was measured. It was seen that pulmonary pressure increases with age. Severe PA hypertension (mean pressure > 40 mm Hg) was found in 14 patients (24.14%), age range was 10-55 years but most of them were more than 20 years old.Bangladesh Heart Journal 2015; 30(1) : 27-28

The effect of oral sildenafil therapy on health-related quality of life in adults with pulmonary arterial hypertension related to uncorrected secundum atrial septal defect: a quasi experimental study

“…Based on the data, we found that the mean age of subjects diagnosed as PAH in uncorrected secundum ASD was 38.72 years. These results are in accordance with the study of Haque et al (2015) which stated that PAH development in secundum ASD mostly occurred in the third decade [ 18 ]. Vogel et al (1999) noted that the incidence of PAH in secundum ASD were increased in patients at the age of 18 to 40 year old [ 19 ].…”

The Effect of Oral Sildenafil Therapy on Health-Related Quality of Life in Adults with Pulmonary Arterial Hypertension related to Uncorrected Secundum Atrial Septal Defect: A Quasi Experimental Study

“…The clinical guidelines do not recommend routine anticoagulant treatment in Eisenmenger syndrome patients and suggest that this therapy may be given in cases of atrial fibrillation and pulmonary artery thrombosis without major haemorrhage. 24 In this study 44,44% (8) with various etiologies such as idiopathic, familial, systemic sclerosis, CHD, human immunodeficiency virus (HIV), liver disease, anorexigen, and obstructive pulmonary venous disease. A total of 93 subjects who were recruited received epoprostenol therapy (28%), bosentan (49%), calcium channel blockers (47%), sildenafil (3%), digoxin (33%), diuretics (57%) and warfarin (49%).…”

“…(2015) which stated that PAH development in secundum ASD mostly occurred in the third decade. 8 Vogel et al (1999) noted that the incidence of PAH in secundum ASD were increased in patients at the age of 18 to 40 year old. 9 The majority of the subjects of this study were female (83.33%) which similar to the previous study.…”