“…The first reports of the validity of PACs were published more than 15 years before the introduction of the Swan-Ganz catheter 2 and almost at the same time as the first serious complication in the form of thrombosis. 3 However, the number of reports accelerated considerably after Swan and Ganz published their studies on the thermodilution PAC in 1970. [4][5] Since its introduction 45 years ago, 4 the flow-directed balloon-tipped PAC has become a monitoring standard and a guide to therapy for patients with critical illnesses undergoing complex or cardiac surgical procedures.…”