1983
DOI: 10.1111/j.1365-2559.1983.tb02270.x
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Pulmonary blastoma, a true congenital neoplasm*

Abstract: An infant, after a difficult delivery, had X-ray shadowing in the right lung. After 32 days sudden death occurred, a pulmonary blastoma being found at autopsy. The controversy over whether this tumour is a blastoma or a carcinosarcoma is discussed and arguments are advanced for acceptance of the designation pulmonary blastoma when the tumour occurs in infancy and childhood. When the equivalent tumour occurs in adults with or without the addition of areas of carcinoma and/or sarcoma, the title 'mixed tumour of … Show more

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Cited by 37 publications
(9 citation statements)
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“…However, the 3 children in our series who had resection at 4 months of age all likely had congenital tumors. In addition, there have been at least 3 previous reports of neonates with PPB and several more with patients diagnosed younger than 6 months, all of whom likely had congenital disease [9,[17][18][19][20][21][22]. Thus, it is clear that PPB should be included in the differential diagnosis of a fetus or infant with a cystic or cystic and solid lung mass, and this possibility should be discussed in family counseling.…”
Section: Discussionmentioning
confidence: 99%
“…However, the 3 children in our series who had resection at 4 months of age all likely had congenital tumors. In addition, there have been at least 3 previous reports of neonates with PPB and several more with patients diagnosed younger than 6 months, all of whom likely had congenital disease [9,[17][18][19][20][21][22]. Thus, it is clear that PPB should be included in the differential diagnosis of a fetus or infant with a cystic or cystic and solid lung mass, and this possibility should be discussed in family counseling.…”
Section: Discussionmentioning
confidence: 99%
“…However, the differences between the groups were not statistically significant, most likely due to the small number of cases (p = .145 in the results, but p = .006 by duplicating the cases). Five cases in this review, all published before 1994, solely relied on traditional hematoxylin-eosin staining and did not perform immunohistochemical staining to achieve the final diagnoses [22][23][24][25][26]. The other nine cases reviewed here all used immunohistochemical methods to make diagnoses.…”
Section: Discussionmentioning
confidence: 99%
“…The other tumor of the lung that may be confused with PPB because of similarities of nomenclature is the pulmonary blastoma (PB) [6,7]. PB is a tumor of adult life, so named because of its supposed resemblance to stages in fetal lung development.…”
Section: Discussionmentioning
confidence: 99%