2023
DOI: 10.1002/mus.27779
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Pulmonary care for ALS: Progress, gaps, and paths forward

Abstract: Introduction Adults with amyotrophic lateral sclerosis (ALS) have been using home mechanical ventilation for over 50 years. More recently, home respiratory care has evolved to include portable home ventilators, airway clearance devices, and physiological assessments with telemonitoring capability. Current State of Respiratory Care National organizations currently offer incentives for providing a pulmonary care specialist within a multidisciplinary ALS clinic; however, several critical gaps exist between the av… Show more

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Cited by 15 publications
(8 citation statements)
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“…Use of NIPPV is related to increased quality of life and survival, 17–19 However, the optimal timing for initiation of ventilatory support in ALS remains controversial 20 . The American Academy of Neurology clinical practice guidelines for ALS recommend consideration for non‐invasive ventilatory support when FVC <50%, MIP less negative than −60 mmHg, or SNIP <40 mmHg 21 .…”
Section: General Changes In Respiratory Function With Nmdsmentioning
confidence: 99%
See 1 more Smart Citation
“…Use of NIPPV is related to increased quality of life and survival, 17–19 However, the optimal timing for initiation of ventilatory support in ALS remains controversial 20 . The American Academy of Neurology clinical practice guidelines for ALS recommend consideration for non‐invasive ventilatory support when FVC <50%, MIP less negative than −60 mmHg, or SNIP <40 mmHg 21 .…”
Section: General Changes In Respiratory Function With Nmdsmentioning
confidence: 99%
“…16 Use of NIPPV is related to increased quality of life and survival, [17][18][19] However, the optimal timing for initiation of ventilatory support in ALS remains controversial. 20 The American Academy of Neurology clinical practice guidelines for ALS recommend consideration for non-invasive ventilatory support when FVC <50%, MIP less negative than À60 mmHg, or SNIP <40 mmHg. 21 However, more recently a Technical Expert Panel convened by the American College of Chest Physiciansrecommended earlier adoptionof NIPPV for patients with restrictive pulmonary disease, including those secondary to neuromuscular weakness, when FVC <80%.…”
Section: Amyotrophic Lateral Sclerosismentioning
confidence: 99%
“…[9][10][11] Accumulating evidence favors aggressive efforts to optimize home assisted ventilation; [12][13][14][15][16] however, professional education and training lag the technical advances in this emerging field, creating an unmet need for up-to-date educational resources. [17][18][19][20] The purpose of this clinical guide is to present a quantitative, physician-directed strategy for managing long-term NIV. We focus on chronic diseases of the respiratory pump that impair breathing including congenital, inflammatory, and degenerative nerve or muscle diseases, traumatic quadriplegia, isolated bilateral diaphragm paralysis, and severe thoracic skeletal disorders such as idiopathic kyphoscoliosis.…”
Section: Introductionmentioning
confidence: 99%
“…Palmieri and Bach for their careful attention to the review article, "Pulmonary Care for ALS: Progress, Gaps, and Paths Forward". 1 Their letter to the editor, "Pulmonary Care for ALS: There is More to the Story", raises several important opinions about the respiratory care of individuals with amyotrophic lateral sclerosis (ALS) that were either omitted or appear to contrast with the perspectives expressed in the original review manuscript. However, the criticism by Drs.…”
mentioning
confidence: 99%