Pulmonary Chemodectomatosis

Minute pulmonary meningothelial-like nodules: clinicopathologic analysis of 121 patients

“…Zak and Chabes [13] originally described MPMNs as multiple nodules and termed this condition chemodectomatosis (minute pulmonary meningothelial-like nodulomatosis). In our examination, multiple MPMNs occurred in 37.2% of all patients with MPMN.…”

“…In some studies, MPMNs were observed 3 times more often in the right lung than in the left [10]. In 1963, Zak and Chabes [13] described the presence of multiple MPMNs in 6 patients and described this condition as chemodectomatosis; therefore, diffuse pulmonary meningotheliomatosis was reported in 2007 [14]. It is not yet clear under what conditions MPMNs frequently occur or whether there is any difference for patients with single or multiple MPMNs.…”

A non-chromaffin paraganglioma of the lung.

“…The discovery of a non-chromaffin paraganglioma in the lung is surprising, because until recently nothing was known about the presence of chemoreceptive tissue in the lung, though there was physiological proof of chemical reflexes in animals. Recently Zak and Chabes (1963) proved that chemoreceptive tissue exists in the neighbourhood of bronchial arteries and the sensitive nerves in the lung of man. Bednar (1966) emphasized the presence of chemoreceptive tissue at the branching of pulmonary venules.…”

“…found in approximately 3% of the normal population, mostly women of middle and advanced age (Zak and Chabes, 1963 …”

“…The achromaffin paragangliomata are more frequent. One of their most usual sites is in the anterior mediastinum in relation to the ascending and the horizontal parts of the aortal arch (Chodkowska and Pawlicka, 1961;Pachter, 1963;Zak and Chabes, 1963 (Pachter, 1963). Their symptomatology is minimal.…”