Pulmonary Coccidioidomycosis in Immunocompetent Patient

Abstract

Coccidioidomycosis is a fungal infection caused by the soil fungus, Coccidioides immitis, which is endemic to the south-western United States. However, the incidence of coccidioidomycosis has recently increased due to the increase in overseas travel to endemic areas. We report a case of pulmonary coccidioidomycosis diagnosed in an immunocompetent person. A 28-year-old female, who had lived in Phoenix, Arizona, USA for 2 years, was admitted for an evaluation of persistent cough with fever lasting for 2 weeks. The chest X-ray and Chest CT revealed multifocal patchy consolidation and ground-glass opacity in both lungs as well as multiple enlarged right hilar and paratracheal lymph nodes. A percutaneous needLe biopsy of the main mass-like consolidation confirmed mature spherules of Coccidioides immitis in lung tissue. Pulmonary coccidioidomycosis should be considered in patients presenting with persistent cough with fever and a history of travel to or immigration from an endemic area.

An Unusual Case of Cavitary Lung Lesion and a Brief Review of Literature

“…In the end, we hypothesized that the DVT was most likely due to apparent trauma in the setting of a hypercoagulable state. DVT was then complicated as PE with infarction, which later cavitated and provided the milieu for lung abscess formation due to secondary infection [7], as suggested by the isolation of Actinomyces odontolyticus. On the other hand, one can argue that Actinomyces infection is the inciting event causing both a hypercoagulable state and pulmonary cavitary lesion.…”

Acute Pulmonary Coccidioidomycosis and Review of Published Cases with Lung Involvement in Korea

“…The pulmonary involvement of coccidioidomycosis was 9 cases, and 3 of them were acute symptomatic disease (Table 1). Most of their chief complaint was fever, and radiologic findings of lung were nodules, consolidation, and effusion [8][9][10][11][12][13][14][15][16].…”