Pulmonary effects of deltamethrin inhalation: an experimental study in rats

Erdoğan, Şeyda; Zeren, E. Handan; Emre, Mustafa; Aydın, Özlem; Gümürdülü, Derya

doi:10.1016/j.ecoenv.2004.10.007

Cited by 28 publications

(15 citation statements)

References 18 publications

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“…A combination of cigarette smoke and alcohol also decreases ciliary beat frequency in bovine primary ciliated bronchial epithelial cells [295]. Chlorocresol, a disinfectant, decreases ciliary beat frequency in human nasal epithelial cells [296] , and the insecticide deltamethrin provokes respiratory ciliary damage in rats [297] . The fungicide benomyl and its metabolites, butyl isocyanate and carbendazim, decrease ciliary beat frequency in canine tracheal epithelial tissue [298] .…”

Section: Cosmetic Ingredients Targeting Autism Genesmentioning

confidence: 99%

Autism genes are selectively targeted by environmental pollutants including pesticides, heavy metals, bisphenol A, phthalates and many others in food, cosmetics or household products

Carter

Blizard

2016

Neurochemistry International

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Section: Cosmetic Ingredients Targeting Autism Genesmentioning

confidence: 99%

Autism genes are selectively targeted by environmental pollutants including pesticides, heavy metals, bisphenol A, phthalates and many others in food, cosmetics or household products

Carter

Blizard

2016

Neurochemistry International

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“…43 For instance, DEL inhalation in experimental animals has been shown to induce prominent pulmonary changes such as emphysema, foamy macrophage accumulation in the alveoli, perivascular inflammation, intraalveolar hemorrhage, peribronchiolar eosinophil predominant inflammatory infiltration, foamy macrophage accumulation in the alveoli, congestion, edema, and thickening of the alveolar septae. 44 Furthermore, insect repellents use in the form of coil is very dreadful because burning of one mosquito coil is found to be equivalent to the smoke produced by burning 75-137 cigarettes. 43 Similarly, in a study on pyrethroid allethrin also showed only lung tissue damage without inducing liver and kidney abnormalities.…”

Section: Discussionmentioning

confidence: 99%

Oxidative stress and neuromodulatory effects of deltamethrin and its combination with insect repellents in rats

Magesh

Anitha

Vijayaraghavan

et al. 2019

Environmental Toxicology

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Deltamethrin (DEL) and other synthetic repellents like N,N‐diethyl benzamide (DEB), N,N‐diethyl phenylacetamide (DEPA), and N,N‐diethyl meta toluamide (DEET) are widely used due their high efficacy against mosquitoes. We evaluated the safe dose on exposure to insecticide and insect repellent individually and in combination in Wistar rats. Rats were administrated with individual chemicals DEL, DEB, DEPA, and DEET and in combination of DEL along DEB, DEPA, and DEET. The reduced glutathione and its detoxifying enzymes were significantly increased in DEL treated rats. Serotonin, dopamine, and noradrenaline were increased in DEL alone and its combination groups. Histopathology revealed that DEL and along with other insect repellants can cause lung toxicities. This study suggests that DEL in combination with other insect repellents showed antagonistic effect against oxidative stress, and there was no significant toxicological effect in the combination groups. The insect repellents with DEL cause less toxic effect and is safe for use.

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“…Alveolar lining cells revealed mild degeneration and a slight hyperplasia in type II cells. Increases in the number of collagen bundles and edema in the alveolar septa were also noted [5,6].…”

Section: Discussionmentioning

confidence: 99%

A Rare Poisoning with Pyrethroid by an Uncommon Route of Self Injection

U¹

2014

Emergency Medicine

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Pyrethroids are structurally modified chemicals of naturally available extract of flower Chrysanthemum cinerariifolium. They are mainly used as insecticide. They are not known to be highly toxic to humans. But some reports of heavy accidental exposure by inhalation or dermal contact have been reported. But this is the first case of attempt of self-harm with pyrethroid that too by self-injection. Here we present a case and review all the toxicity of pyrethroids reported.

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Pulmonary effects of deltamethrin inhalation: an experimental study in rats

Cited by 28 publications

References 18 publications

Autism genes are selectively targeted by environmental pollutants including pesticides, heavy metals, bisphenol A, phthalates and many others in food, cosmetics or household products

Autism genes are selectively targeted by environmental pollutants including pesticides, heavy metals, bisphenol A, phthalates and many others in food, cosmetics or household products

Oxidative stress and neuromodulatory effects of deltamethrin and its combination with insect repellents in rats

A Rare Poisoning with Pyrethroid by an Uncommon Route of Self Injection

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